Cardiac injury after subarachnoid hemorrhage is independent of the type of aneurysm therapy
Cardiac injury after subarachnoid hemorrhage is independent of the type of aneurysm therapy
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DOI：
10.1227/01.neu.0000143165.50444.7f
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发表时间：
2004-12-01
期刊：
影响因子：
4.8
通讯作者：
Zaroff, JG
中科院分区：
文献类型：
--
作者：
Miss, JC;Kopeinik, A;Zaroff, JG
目的：蛛网膜下腔出血(SAH)与心脏损伤和功能障碍有关。对于SAH后肌钙蛋白释放和左心功能不全的风险，夹闭术和弹簧圈是否有不同的影响尚不清楚。假设动脉瘤治疗不影响发生心脏损伤和功能障碍的风险。方法：本研究包括172例SAH患者，他们接受夹闭(n=109)或弹簧圈(n=63)治疗。在入选后第1、3、6天收集血流动力学数据，测定心肌肌钙蛋白I，并进行超声心动图检查。心肌肌钙蛋白I测定超过1.0ug/L被认为是异常。对于每一次超声心动图检查，盲人观察者测量左心室射血分数(如果
OBJECTIVE: Subarachnoid hemorrhage (SAH) is associated with cardiac injury and dysfunction. Whether aneurysm clipping versus coiling has a differential effect on the risk of troponin release and left ventricular (LV) dysfunction after SAH is unknown. It is hypothesized that aneurysm treatment does not affect the risk of developing cardiac injury and dysfunction.METHODS: The study included 172 consecutive SAH patients who underwent clipping (n = 109) or coiling (n = 63) aneurysm therapy. Hemodynamic data were collected, cardiac troponin I was measured, and echocardiography was performed on the 1 st, 3rd, and 6th days after enrollment. A cardiac troponin I measurement of more than 1.0 mug/L was considered abnormal. For each echocardiographic examination, a blinded observer measured LV ejection fraction (abnormal if