Synthetic studies toward anisatin:: A formal synthesis of (±)-8-deoxyanisatin

Synthetic studies toward anisatin:: A formal synthesis of (±)-8-deoxyanisatin
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DOI:
10.1021/ol006918c
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发表时间:
2001-01-25
期刊:
影响因子:
5.2
通讯作者:
Hu, QY
Hu, QY
中科院分区:
化学1区
文献类型:
--
作者:
Loh, TP;Hu, QY

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[GRAPHICS]An efficient strategy to construct the congested C-7a quaternary chiral center of anisatin was developed, by way of an Eschenmoser-Claisen rearrangement, Conversion of the resultant amide to Kende's epsilon -lactone intermediate 3 in four steps completed a concise formal synthesis of (+/-)-8-deoxyanisatin (2).