Assessment of aloe vera for qualitative fit testing of particulate respirators: a logistic regression approach
Assessment of aloe vera for qualitative fit testing of particulate respirators: a logistic regression approach
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DOI：
10.2486/indhealth.2109-0019
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发表时间：
2020-01-01
影响因子：
2
通讯作者：
Banaee, Sean
中科院分区：
文献类型：
--
作者：
Fakherpour, Anahita;Jahangiri, Mehdi;Banaee, Sean
过滤面式呼吸器(FFR)需要配合测试程序，以确定皮肤和面罩密封面之间的可接受配合。本研究试图比较芦荟(A.vera)和商用Bitrex(TM)作为颗粒呼吸器定性适合性测试的挑战剂的有效性。研制了一种由七种不同浓度的芦荟组成的中草药溶液。对金黄色葡萄球菌溶液的阈值筛选试验(TSTs)与Bitrex(TM)进行了比较。为了做到这一点，对总共62名参与者随机给予了溶液。一种安慰剂也进行了测试，以确保味觉反应有效。采用R 3.2.5.0软件进行统计分析。在Avera(41.7、58.3、75和91.7 mg/ml)和Bitrex(TM)阈值测试之间没有统计学上的显著差异。因此，开发该阈值溶液的最低黄曲霉浓度被认为是41.7 mg/ml。当商业产品价格昂贵且无法获得时，一种经济有效的技术将是用商业产品代替黄曲霉溶液作为口罩LIT定性检测的挑战剂。
Fit testing procedure is required for filtering facepiece respirators (FFRs) to ascertain an acceptable fit between the skin and facepiece sealing surface. The present study seeks to compare the efficacy of Aloe vera (A. vera) and commercial Bitrex (TM) as challenge agents of qualitative fit testing of particulate respirators. An herbal solution consisting of A. vera at seven different concentrations was developed. Threshold Screening Tests (TSTs) of A. vera solutions were compared to Bitrex (TM). To do so, solutions were administered randomly on a total of 62 participants. A placebo was also tested to ensure the taste response being valid. Statistical analysis was performed using R 3.2.5.0 software. There were no statistically significant differences between the A. vera (41.7, 58.3, 75, and 91.7 mg/ml) and Bitrex (TM) threshold tests. Therefore, the minimum concentration of A. vera to develop the threshold solution was considered to he 41.7 mg/ml. When commercial products are expensive and unavailable, a cost-effective technique would be to replace A. vera solution with a commercial product as a challenge agent of qualitative lit testing of respirators.