Feasibility of replacing homemade solutions by commercial products for qualitative fit testing of particulate respirators: a mixed effect logistic regression study

Feasibility of replacing homemade solutions by commercial products for qualitative fit testing of particulate respirators: a mixed effect logistic regression study
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DOI:
10.1016/j.mex.2019.05.034
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发表时间:
2019-01-01
期刊:
影响因子:
1.9
通讯作者:
Seif, Mozhgan
Seif, Mozhgan
中科院分区:
其他
文献类型:
--
作者:
Fakherpour, Anahita;Jahangiri, Mehdi;Seif, Mozhgan

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为了确保佩戴者在进入受污染的工作场所之前正确佩戴,必须对紧贴式呼吸器进行定性适配测试。这项研究的目的是评价自制溶液作为商业产品的替代产品对微粒口罩的定性适合性测试。Bitrex(TM)和糖精两种自制溶液是根据职业安全与健康管理局(OSHA)第29 CFR 1910.134条规定制造的。对62名参与者按随机顺序进行了商业解决方案和自制解决方案的阈值筛选测试(TST)。一种安慰剂也进行了测试,以确保参与者能够将其无味与其他味道的溶液区分开来。商业解决方案和自制解决方案之间没有统计上的显著差异,即参与者感受到了Bitrex(TM)的苦味和糖精解决方案的甜味(分别为96.8%比91.9%和93.5%比83.9%)。在过滤面式呼吸器(FFR)的定性适合性测试中,可以用稳定且不含微生物污染的自制溶液代替商品产品。总体而言,该协议提出了一种实用且成本效益高的技术来评估FFR的适合性测试。(C)2019年提交人。爱思唯尔出版公司(Elsevier B.V.)
Qualitative fit testing is mandatory for tight-fitting respirators to ensure that the wearer fitted properly before entering a contaminated workplace. The purpose of this study was to evaluate the homemade solutions as substitution of commercial products for qualitative fit testing of particulate respirators. Two homemade solutions of Bitrex (TM) and saccharin were made according to the Occupational Safety and Health Administration (OSHA) regulation 29 CFR 1910.134. Threshold Screening Tests (TSTs) of commercial solutions, as well as homemade ones, were conducted on 62 participants in a random order. A placebo was also tested to assure the participants could distinguish its flavorless from other taste of solutions. There were no statistically significant differences between the commercial and homemade solutions representing that participants detected the bitter taste of the Bitrex (TM) and sweet taste of the saccharin solutions (96.8% vs. 91.9% and 93.5% vs. 83.9%, respectively). Homemade solutions that were stable and haven't been contained microbial contaminations, could be substituted for commercial products in qualitative fit testing of filtering face-piece respirators (FFRs). Overall, this protocol presents a practical and cost-benefit technique to assess the fit testing of FFRs. (C) 2019 The Authors. Published by Elsevier B.V.