Using FM1-43 to study neuropeptide granule dynamics and exocytosis
Using FM1-43 to study neuropeptide granule dynamics and exocytosis
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DOI：
10.1016/j.ymeth.2004.01.002
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发表时间：
2004-08-01
期刊：
影响因子：
4.8
通讯作者：
Betz, WJ
中科院分区：
文献类型：
--
作者：
Brumback, AC;Lieber, JL;Betz, WJ
在神经肽分泌和膜运输的研究中，荧光染料FM 1 -43提供了选择性地标记那些在活细胞中真实的时间内经历胞吐和胞吞作用的结构的能力。本文综述了FM染料的独特性质，使其成为研究神经肽颗粒动力学的理想选择，并讨论了利用FM染料的各种技术。(C)2004爱思唯尔公司All rights reserved.
In the study of neuropeptide secretion and membrane trafficking, the fluorescent dye FM1-43 provides the ability to label selectively those structures that are undergoing exocytosis and endocytosis in living cells in real time. This review describes the unique properties of the FM dyes that make them ideal for studying neuropeptide granule dynamics and discusses various techniques that take advantage of FM dyes. (C) 2004 Elsevier Inc. All rights reserved.