Cortical mapping of auditory-evoked offset responses in rats
Cortical mapping of auditory-evoked offset responses in rats
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DOI：
10.1097/01.wnr.0000134848.63755.5c
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发表时间：
2004-07
期刊：
影响因子：
1.7
通讯作者：
Hirokazu Takahashi;M. Nakao;K. Kaga
中科院分区：
文献类型：
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作者：
Hirokazu Takahashi;M. Nakao;K. Kaga
本研究采用多点表面微电极记录方法，观察了大鼠听觉皮层的电刺激诱发偏移反应。短纯音用作测试刺激。偏移反应没有出现tonotopically，但在tonotopic的发病分布的边缘。偏移幅度显着敏感的声音强度，下降时间在音调终止，持续时间。这些结果表明，偏移反应与兴奋性起始反应周围的抑制反应，偏移反应变得大时，抑制变得强，长或同步终止。因此，在刺激存在下抑制后的反弹可能是听觉皮层中偏移反应的主要原因。
We characterized the auditory-evoked offset responses of the rat auditory cortex by multiple-site surface microelectrode recording. Tone bursts served as test stimuli. Offset responses did not appear tonotopically, but at the fringe of tonotopic onset distributions. Offset amplitude was significantly sensitive to sound intensity, fall time at tone termination, and duration. These results suggest that offset responses are associated with inhibitory responses surrounding excitatory onset responses, and offset responses become large when inhibition becomes strong and long or terminates synchronously. Thus, the rebound after the inhibition in the presence of a stimulus is likely to be a major cause of offset responses in the auditory cortex.