Complex Polymer Architectures Using Ring-Opening Metathesis Polymerization: Synthesis, Applications, and Practical Considerations
Complex Polymer Architectures Using Ring-Opening Metathesis Polymerization: Synthesis, Applications, and Practical Considerations
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DOI：
10.1021/acs.macromol.2c00338
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发表时间：
2022-06-14
期刊：
影响因子：
5.5
通讯作者：
Matson, John B.
中科院分区：
文献类型：
--
作者：
Blosch, Sarah E.;Scannelli, Samantha J.;Matson, John B.
大自然向我们展示了复杂的分子结构导致独特的材料特性，这些观察结果促使聚合物科学家合成复杂的结构，以发现拓扑结构如何影响合成聚合物的特性。在这个角度来看，我们讨论了各种复杂的结构，使用开环易位聚合（ROMP），包括多嵌段线性聚合物，瓶刷均聚物和（多）嵌段共聚物，树枝状聚合物，星星聚合物，和聚合物-生物分子共轭物。传统的和最近开发的合成方法，包括聚合诱导的自组装，共聚，以创建梯度结构，和工程方法，使复杂的拓扑结构，使用开环易位聚合，也进行了审查。在这方面，我们强调了这些材料的新兴应用，包括药物输送载体，纳米结构，以及光折射或能量存储组件等。最后，我们得出结论，在ROMP的实际考虑，使最高水平的控制时，从空间要求或其他挑战性（大）单体合成复杂的聚合物拓扑结构的深入讨论。我们希望这一观点将指导科学家合成复杂的聚合物结构，以获得具有独特性能和应用潜力的新型创新材料。
Nature shows us that complex molecular architectures lead to unique material properties, and these observations have driven polymer scientists to synthesize complex architectures in an effort to discover how topology influences properties in synthetic polymers. In this Perspective, we discuss a variety of complex architectures synthesized using ring-opening metathesis polymerization (ROMP), including multiblock linear polymers, bottlebrush homopolymers and (multi)block copolymers, dendronized polymers, star polymers, and polymer-biomolecule conjugates. Traditional and recently developed synthetic methods, including polymerization-induced self-assembly, copolymerization to create gradient structures, and engineering approaches to making complex topologies using ROMP, are also reviewed. In this context, we highlight emerging applications stemming from these materials, including drug delivery vehicles, nanoscale constructs, and components in light refraction or energy storage, among others. Finally, we conclude with an in-depth discussion on practical considerations in ROMP that enable the highest level of control when synthesizing complex polymer topologies from sterically demanding or otherwise challenging (macro)monomers. Our hope is that this Perspective will guide scientists synthesizing complex polymer architectures toward new and innovative materials with the potential for unique properties and applications.