Influence of root canal dressings and sealers on repair of apical periodontitis after endodontic treatment
Influence of root canal dressings and sealers on repair of apical periodontitis after endodontic treatment
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DOI：
10.1067/moe.2002.117803
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发表时间：
2002-02-01
影响因子：
--
通讯作者：
Bramante, CM
中科院分区：
文献类型：
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作者：
Berbert, FLCV;Leonardo, MR;Bramante, CM
目标。本研究的目的是评价2种氢氧化钙根管敷料和2种根管封闭剂对慢性根尖周炎坏死牙根管治疗后根尖周组织的组织病理学反应。用5.25%次氯酸钠冲洗液对78个根管进行预备，然后用氢氧化钙糊剂(Calen/PMCC或Calasept)进行30天的敷料。然后使用冷侧牙胶凝固剂和封闭封闭剂(Sealtex或AH Plus)充填根管。360d后，麻醉过量处死动物，制作组织学标本，切片，苏木精-伊红染色，光镜下观察根尖及根尖周组织修复情况。统计分析显示，Calasept/AH Plus组的组织病理学结果最差，而Sealtex封闭剂总体上比AH Plus封闭剂有更好的根尖修复效果。Calen/PMCC糊剂与Calasept糊剂的组织病理学结果差异有统计学意义，但Calen/PMCC糊剂加AH Plus与Calasept糊剂加AH Plus的结果不同。实验结果表明，用2种氢氧化钙根管敷料和2种封闭剂对慢性根尖周炎患牙进行根尖和根尖周组织修复的效果不同。有必要进行更多的研究，以确定敷料和封闭剂的最佳组合。
Objective. The objective of this study was to evaluate the histopathologic response of periapical tissues after root canal treatment of necrotic dog teeth with chronic apical periodontitis by using 2 calcium hydroxide-based root canal dressings and 2 root canal sealers.Study design. Seventy-eight root canals were instrumented by using 5.25% sodium hypochlorite as the irrigating solution, after which a calcium hydroxide paste (Calen/PMCC or Calasept) was placed for 30 days as a dressing. The root canals were then filled by using cold lateral gutta-percha condensation and an enclodontic sealer (Sealapex or AH Plus). After 360 days, the animals were killed by anesthetic overdose; then, the teeth were histologically prepared, sectioned, and stained with hematoxylin and eosin for optical microscopic analysis of apical and periapical tissue repair.Results. Statistical analysis showed that the poorest histopathologic results were observed in the Calasept/AH Plus group and that the Sealapex sealer overall resulted in better apical repair than the AH Plus sealer. The histopathologic results of Calen/PMCC paste with both AH Plus and Sealapex and Calasept paste with only Sealapex were statistically similar but were different from the results of Calasept with AH Plus.Conclusions. The results of this study in the dog showed differences in apical and periapical tissue repair of teeth with chronic apical periodontitis by using 2 calcium hydroxide root canal dressings and 2 sealers. More research is necessary to determine the best combination of dressings and sealers.