Norovirus infection as a cause of sporadic healthcare-associated diarrhoea.
Norovirus infection as a cause of sporadic healthcare-associated diarrhoea.
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诺如病毒感染是导致散发性医疗相关腹泻的原因。
DOI：
10.1016/j.jhin.2009.03.010
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
DuPont,HL
中科院分区：
文献类型：
--
作者：
Koo,HL;Ajami,NJ;Jiang,Z-D;Atmar,RL;DuPont,HL
医疗保健相关性腹泻是世界范围内一种重要的医院疾病。在大多数病例中，与医疗保健相关的腹泻的病因尚不明确。艰难梭菌(Clostridium Difficile，CD)是唯一一种常见的引起健康相关腹泻的肠道病原体，但仅在15%-20%的医院腹泻发作中被检测到。1诺沃克病毒(11月)胃肠炎在医疗机构的暴发已有充分的记录。2、3然而，在非流行环境中，散发性新城疫感染作为成人卫生保健相关腹泻的一个原因的流行率尚未确定。由于其环境稳定性、对大多数清洁剂的抗药性以及临床康复后长时间的粪便排泄，4NOV可能是健康相关性腹泻的病原体。这项研究旨在调查德克萨斯州休斯敦一家大型三级大学医院11月份零星医院腹泻的流行率。
Healthcare-associated diarrhea is an important nosocomial disease worldwide. The etiologic agent of healthcare-associated diarrhea is undefined in the majority of cases. Clostridium difficile (CD) is the only enteric pathogen regularly identified as a cause of healthcareassociated diarrhea, but is detected in only 15-20% of nosocomial diarrhea episodes. 1Norovirus (NoV) gastroenteritis outbreaks in healthcare facilities have been welldocumented. 2, 3 However, the prevalence of sporadic NoV infections as a cause of healthcare-associated diarrhea in adults, in a non-epidemic setting, has not been established. With their environmental stability, resistance to most cleaning agents, and prolonged fecal excretion after clinical recovery, 4 NoVs may play a role as a pathogen of healthcareassociated diarrhea. This study was designed to investigate the prevalence of sporadic NoV nosocomial diarrhea at a large tertiary university-based hospital in Houston, Texas.