Progressive Multifocal Leukoencephalopathy and Relapsing-Remitting Multiple Sclerosis
Progressive Multifocal Leukoencephalopathy and Relapsing-Remitting Multiple Sclerosis
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DOI：
10.1001/archneurol.2009.31
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发表时间：
2009-05-01
影响因子：
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通讯作者：
Khan, Omar
中科院分区：
文献类型：
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作者：
Boster, Aaron;Hreha, Stephanie;Khan, Omar
目的：目的：确定临床和磁共振成像（MRI）特征，以区分进行性多灶性白质脑病（PML）和复发缓解型多发性硬化（RRMS）。设计：回顾性病历回顾。背景：密歇根州底特律市的两所城市教学医院。患者：45例确诊的PML病例和100例RRMS患者。主要结果指标：临床和MRI特征区分PML和RRMS。结果：总的来说，多发性硬化症（MS）的单一症状表现比PML更常见（85%比47%; P
Objective: To identify clinical and magnetic resonance imaging (MRI) features that distinguish progressive multifocal leukoencephalopathy (PML) from relapsing-remitting multiple sclerosis (RRMS).Design: Retrospective medical record review.Setting: Two urban teaching hospitals in Detroit, Michigan.Patients: Forty-five confirmed PML cases and 100 patients with RRMS.Main Outcome Measures: Clinical and MRI features distinguishing PML from RRMS.Results: Overall, monosymptomatic presentations were more common in multiple sclerosis (MS) than PML (85% vs 47%; P