Identification and characterization of bocaviruses in cats and dogs reveals a novel feline bocavirus and a novel genetic group of canine bocavirus
Identification and characterization of bocaviruses in cats and dogs reveals a novel feline bocavirus and a novel genetic group of canine bocavirus
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DOI：
10.1099/vir.0.042531-0
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发表时间：
2012-07-01
影响因子：
3.8
通讯作者：
Yuen, Kwok-Yung
中科院分区：
文献类型：
--
作者：
Lau, Susanna K. P.;Woo, Patrick C. Y.;Yuen, Kwok-Yung
我们报告了一种新的博卡病毒，猫博卡病毒(FBoV)和与犬博卡病毒(CBoV)CON-161株密切相关的新博卡病毒在香港流浪猫和狗身上的鉴定和基因组特征。364只猫的粪便、鼻腔、尿液、肾脏和血液标本中，FBoV的检出率分别为7.2%、0.3%、1.6%、2.0%和0.8%；351只犬的粪便、鼻腔、尿液和血液中检出CBoV的比例分别为4.6%、5.1%、6.3%和0.3%。对三个FBoV基因组进行测序发现，存在三个具有博卡病毒特征的ORF。系统发育分析表明，FBoV与其他博卡病毒只有很远的亲缘关系，在该属内形成了一个独特的簇，
We report the identification and genome characterization of a novel bocavirus, feline bocavirus (FBoV), and novel bocaviruses closely related to canine bocavirus (CBoV) strain Con-161 in stray cats and dogs in Hong Kong, respectively. FBoV was detected by PCR in 7.2, 0.3, 1.6, 2.0 and 0.8% of faecal, nasal, urine, kidney and blood samples, respectively, from 364 cats, while CBoV was detected in 4.6, 5.1, 6.3 and 0.3% of faecal, nasal, urine and blood samples, respectively, from 351 dogs. Three FBoV genomes sequenced revealed the presence of three ORFs characteristic of bocaviruses. Phylogenetic analysis showed that FBoVs were related only distantly to other bocaviruses, forming a distinct cluster within the genus, with