Odors released by stressed rats produce opioid analgesia in unstressed rats.
Odors released by stressed rats produce opioid analgesia in unstressed rats.
复制标题
应激大鼠释放的气味会在未应激大鼠中产生阿片类镇痛作用。
DOI：
10.1037//0735-7044.99.3.589
复制
发表时间：
1985
影响因子：
1.9
通讯作者：
Michael S. Fanselow
中科院分区：
文献类型：
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作者：
Michael S. Fanselow
当未受压力的大鼠被放置在一个含有受到电击的同种动物气味的房间中时，通过福尔马林试验评估，它们变得止痛。非应激同种和新气味的气味没有产生这样的效果。这种镇痛作用可被纳洛酮逆转。这些数据表明，自然刺激与厌恶的环境事件天生相关，可以激活内源性疼痛控制机制。
When unstressed rats were placed in a chamber containing the odor of a conspecific that had received electric shock, they became analgesic as assessed by the formalin test. The odors of nonstressed conspecifics and novel odors produced no such effect. This analgesia was reversed by naltrexone. The data suggest that naturalistic stimuli innately associated with aversive environmental events can activate endogenous pain control mechanisms.