Is the adiposity rebound a rebound in adiposity?
Is the adiposity rebound a rebound in adiposity?
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DOI：
10.3109/17477166.2010.526613
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发表时间：
2011-06-01
影响因子：
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通讯作者：
Wake, Melissa
中科院分区：
文献类型：
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作者：
Campbell, Michele Wen-Chien;Williams, Joanne;Wake, Melissa
客观的。早期肥胖反弹（[AR]，当体重指数 [BMI] 在达到最低点后上升）强烈预示着以后的肥胖。我们研究了 AR 时 BMI 的上升是否伴随着体脂的增加。设计。基于社区的队列研究。科目。共有 299 名头生子女（49% 为男性）。测量。每六个月进行一次人体测量和生物电阻抗，4-6.5 年；瘦肉和脂肪质量指数 (kg/m(2)) 可与 BMI 直接比较。补充（0-2 岁）体重和身长测量（生长曲线建模所需）取自受试者的儿童健康记录。方法。 AR 是根据从出生到 6.5 岁的单独建模 BMI 曲线估算的。进行了两项主要分析：1）早期（5年）反弹儿童的BMI、脂肪质量指数（FMI）、瘦体重指数（LMI）和体脂百分比的横断面比较； 2) AR前后BMI、FMI、LMI和体脂百分比线性趋势的调查。结果。 81 名经历早期 AR 的儿童 (27%) 在 6.5 岁时有较高的 BMI、FMI、LMI 和脂肪百分比。总体而言，FMI 在 AR 前急剧下降，为每年 -0.56 (0.02) kg/m(2)（平均[标准误差]），然后在 AR 后趋于平缓至每年 0.07 (0.05) kg/m(2)。相比之下，LMI 在 AR 前增加（0.34 [0.01]），在 AR 后变陡（每年 0.47 [0.03] kg/m(2)）。结论。 “肥胖反弹”的特点是去脂质量指数增加，同时脂肪质量指数停止下降。了解控制儿童身体成分动态的因素以及延迟 AR 的机制有助于预防肥胖。
Objective. Early adiposity rebound ([AR], when body mass index [BMI] rises after reaching a nadir) strongly predicts later obesity. We investigated whether the upswing in BMI at AR is accompanied by an increase in body fat. Design. Community-based cohort study. Subjects. A total of 299 first-born children (49% male). Measurements. Six-monthly anthropometry and bioelectrical impedance, 4-6.5 years; lean and fat mass index (kg/m(2)) for direct comparison with BMI. Supplementary (0-2 years) weight and length measures (needed for growth curve modelling) were drawn from subjects' child health records. Methods. AR was estimated from individually modelled BMI curves from birth to 6.5 years. Two main analyses were performed: 1) cross-sectional comparisons of BMI, fat mass index (FMI), lean mass index (LMI) and percent body fat in children with early (5 years) rebound; and 2) investigation of linear trends in BMI, FMI, LMI and percent body fat before and after AR. Results. The 81 children (27%) experiencing early AR had higher BMI, FMI, LMI and percent fat at 6.5 years. Overall, FMI decreased steeply pre-AR, at -0.56 (0.02) kg/m(2) per year (mean [Standard Error]), then flattened post-AR to 0.07 (0.05) kg/m(2) per year. In contrast, LMI increased pre-AR (0.34 [0.01]) and steepened post-AR (0.47 [0.03] kg/m(2) per year). Conclusion. The 'adiposity rebound' is characterised by increasing lean mass index, coupled with cessation of the decline in fat mass index. Understanding what controls the dynamics of childhood body composition and mechanisms that delay AR could help prevent obesity.