Genetic syndromes among individuals with mental retardation
Genetic syndromes among individuals with mental retardation
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DOI：
10.1002/ajmg.a.20492
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发表时间：
2003-11-15
影响因子：
2
通讯作者：
Collins, JS
中科院分区：
文献类型：
--
作者：
Stevenson, RE;Procopio-Allen, AM;Collins, JS
智力迟钝的人比没有智力迟钝的人更常见畸形和其他结构异常。在许多情况下，相关的异常包括由遗传或环境损伤引起的可识别的综合征。因此，结构异常与精神发育迟滞的共同发生有助于诊断评估，特别是在婴儿和幼儿中。结构和精神异常的共存也表明两者都起源于胚胎发育期。(C)2003 Wiley-Liss，Inc.
Individuals with mental retardation more commonly have malformations and other structural anomalies than individuals without mental retardation. In many cases, the associated anomalies comprise recognizable syndromes caused by genetic or environmental insults. To co-occurrence of structural anomalies with mental retardation thus assists in the diagnostic evaluation, particularly in infants and young children. The coexistence of structural and mental abnormalities also suggests that both originated in the embryonic period of development. (C) 2003 Wiley-Liss, Inc.