Knowledge and awareness of nonpharmacist salespersons regarding over-the-counter drug use in patients with chronic kidney disease in Japan
Knowledge and awareness of nonpharmacist salespersons regarding over-the-counter drug use in patients with chronic kidney disease in Japan
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DOI：
10.1371/journal.pone.0213763
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发表时间：
2019-03-20
期刊：
影响因子：
3.7
通讯作者：
Irie, Tetsumi
中科院分区：
文献类型：
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作者：
Kondo, Yuki;Ishitsuka, Yoichi;Irie, Tetsumi
慢性肾脏病（CKD）患者依赖于医疗保健专业人员的建议，以避免使用不合适的非处方（OTC）药物。最近，合格的、注册的非药剂师销售人员获得了在日本销售OTC药物的许可。然而，注册销售人员的知识和意识的注意事项，不适合用于CKD患者的OTC药物还不清楚。ObjectivesThis study aimed to clarify the awareness，知识，和实施的注意事项注册销售人员关于CKD患者使用的OTC药物。此外，我们评估了注册销售人员的知识和意识的变化，这一主题所产生的药剂师intervention.MethodsA问卷调查和药剂师干预，适用于175名注册销售人员。干预包括由一位接受过肾脏病学培训的药剂师进行的50分钟讲座。知识，意识和实施的预防措施，参与者就非甾体抗炎药（NSAID）和抗酸剂进行了评估之前和之后intervention. ResultsAbout一半的注册销售人员报告以前的经验与销售OTC药物，不适合CKD患者（NSAID，48.0%;抗酸剂，39.7%）。很少有参与者认识到在向这些患者出售这些药物时需要检查肾功能（NSAID，25.7%;抗酸剂，47.5%）。干预后注册销售人员对非处方药的知晓率和知识掌握率均显著高于干预前。结论：干预前注册销售人员对非处方药在CKD患者中的使用知晓率和知识掌握率较低，尽管他们有销售非处方药的经验。但是，药师干预提高了注册销售人员的意识和知识。对注册销售人员的教育计划可能是必要的，以防止CKD患者不适当地使用OTC药物。
IntroductionPatients with chronic kidney disease (CKD) depend on advice from healthcare professionals to avoid using unsuitable over-the-counter (OTC) drugs. Recently, qualified, registered non-pharmacist salespersons became licensed to sell OTC drugs in Japan. However, registered salespersons' knowledge and awareness of precautions regarding unsuitable OTC drugs for use in patients with CKD are unclear.ObjectivesThis study aimed to clarify the awareness, knowledge, and implementation of precautions by registered salespersons regarding OTC drugs used by patients with CKD. Additionally, we evaluated the change of registered salespersons' knowledge and awareness of this topic generated by a pharmacist intervention.MethodsA questionnaire survey and pharmacist intervention were applied to 175 registered salespersons. The intervention comprised a 50-minute lecture imparted by a pharmacist who was trained in nephrology. The knowledge, awareness, and implementation of precautions by participants with respect to nonsteroidal anti-inflammatory drugs (NSAIDs) and antacids were evaluated before and after the intervention.ResultsApproximately half of the registered salespersons reported previous experience with selling OTC drugs that were inappropriate for patients with CKD (NSAIDs, 48.0%; antacids, 39.7%). Few participants recognized the need to check renal function when selling those drugs to such patients (NSAIDs, 25.7%; antacids, 47.5%). The registered salespersons' awareness and knowledge were significantly higher after the intervention than before it.ConclusionThe results indicate that before the intervention, the registered salespersons had low levels of awareness and knowledge regarding OTC drug use in patients with CKD despite having prior experience selling unsuitable OTC drugs. However, the pharmacist intervention improved the registered salespersons' awareness and knowledge. The educational program for registered salespersons might be necessary to prevent inappropriate OTC drug use by patients with CKD.