New sesquiterpenoids from Petasites japonicus and Petasites tricholobus
New sesquiterpenoids from Petasites japonicus and Petasites tricholobus
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来自蜂斗菜和毛叶蜂斗菜的新倍半萜类化合物
DOI：
10.1016/j.phytol.2017.10.008
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发表时间：
2017
影响因子：
1.7
通讯作者：
Fei Wang
中科院分区：
文献类型：
--
作者：
Ping Hai;Yuan Gao;Chun-Gui Xiao;Xiang-Mei Li;Wan-Qiu Yang;Rong-Tao Li;Fei Wang
对蜂斗菜和毛裂蜂斗菜的全株进行植物化学研究，分离出五种新的bakkenolide型倍半萜，即bakkenolide-Ib（1）、bakkenolide-IIb（2）、bakkenolide-IIIb（3）、bakkenolide-IVb（4）和bakkenolide-Vb（5），以及一种新的eremophilane型降倍半萜，petasindiol（6）。其结构经NMR和HRESIMS分析确证。Petasindiol（6）是首次从蜂斗菜属植物中分离得到的15-noreremophilane倍半萜类化合物。
Phytochemical investigation of the whole plants of Petasites japonicus and Petasites tricholobus led to the isolation of five new bakkenolide-type sesquiterpenoids, bakkenolide-Ib (1), bakkenolide-IIb (2), bakkenolide-IIIb (3), bakkenolide-IVb (4), and bakkenolide-Vb (5), and a new eremophilane-type norsesquiterpenoid, petasindiol (6). Their structures were elucidated by NMR and HRESIMS analyses. Petasindiol (6) represented the first example of 15-noreremophilane sesquiterpenoid from the genus Petasites.