LEUKOENCEPHALOPATHY AND MAJOR DEPRESSION - A PRELIMINARY-REPORT
LEUKOENCEPHALOPATHY AND MAJOR DEPRESSION - A PRELIMINARY-REPORT
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DOI：
10.1016/0925-4927(92)90024-x
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发表时间：
1992-11-01
影响因子：
2.3
通讯作者：
SZUBA, MP
中科院分区：
文献类型：
--
作者：
GUZE, BH;SZUBA, MP
研究人员对 119 名年轻和老年住院和门诊重度抑郁症患者的白质脑病变化的比较患病率进行了检查。患者接受 T1 和 T2 加权脉冲序列的磁共振成像 (MRI) 检查。白质脑病改变在抑郁症患者和 45 岁以下的医学对照受试者中并不常见。然而，大约 44% 的老年抑郁症患者和 30% 的老年医学对照受试者中出现了这种变化。
The comparative prevalence of leukoencephalopathic changes in 119 young and old inpatients and outpatients with major depression was examined. Patients underwent magnetic resonance imaging (MRI) examinations with T1-and T2-weighted pulse sequences. Leukoencephalopathic changes were uncommon in depressed patients and medical control subjects younger than 45 years of age. Such changes were, however, seen in approximately 44% of older depressed patients and 30% of elderly medical control subjects.