The role of the dorsolateral prefrontal cortex in deception when remembering neutral and emotional events
The role of the dorsolateral prefrontal cortex in deception when remembering neutral and emotional events
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DOI：
10.1016/j.neures.2010.11.001
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发表时间：
2011-02-01
影响因子：
2.9
通讯作者：
Mori, Etsuro
中科院分区：
文献类型：
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作者：
Ito, Ayahito;Abe, Nobuhito;Mori, Etsuro
我们使用功能磁共振成像(FMRI)来研究在记住中性事件和情绪事件时欺骗的神经关联。在功能磁共振成像之前，受试者被展示了一系列中性和情绪化的图片，并被要求对每一张图片的唤醒程度进行评级。在功能磁共振成像过程中，受试者被呈现给研究过的和未研究过的图片，并被要求对一半的图片做出诚实的识别判断，对另一半的图片做出不诚实的反应。我们发现，与中性图片记忆有关的欺骗与双侧背外侧前额叶皮质、左侧腹外侧额叶皮质和左侧眼眶前额叶皮质的活动增加有关。我们还发现，记忆情绪图片时的欺骗与双侧背外侧前额叶皮质的活动增加有关。在双侧背外侧前额叶皮质中发现了两种类型的欺骗之间的重叠激活。我们的结果表明，背外侧前额叶皮质与欺骗的执行方面有关，与记忆内容的情感价位无关。(C)2010年爱思唯尔爱尔兰有限公司和日本神经科学学会。版权所有。
We used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of deception while remembering neutral events and emotional events. Before fMRI, subjects were presented with a series of neutral and emotional pictures and were asked to rate each picture for arousal. During fMRI, subjects were presented with the studied and nonstudied pictures and were asked to make an honest recognition judgment in response to half of the pictures and a dishonest response to the remaining half. We found that deception pertaining to the memory of neutral pictures was associated with increased activity in the bilateral dorsolateral prefrontal cortex, the left ventrolateral prefrontal cortex, and the left orbitofrontal cortex. We also found that deception while remembering emotional pictures was associated with increased activity in the bilateral dorsolateral prefrontal cortex. An overlapping activation between the two types of deception was found in the bilateral dorsolateral prefrontal cortex. Our results indicate that the dorsolateral prefrontal cortex is associated with the executive aspects of deception, regardless of the emotional valence of memory content. (C) 2010 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.