Language-related brain function during word repetition in post-stroke aphasics
Language-related brain function during word repetition in post-stroke aphasics
复制标题
DOI：
10.1097/00001756-200408260-00011
复制
发表时间：
2004-08-26
期刊：
影响因子：
1.7
通讯作者：
Yonemoto, K
中科院分区：
文献类型：
--
作者：
Abo, M;Senoo, A;Yonemoto, K
我们比较了功能磁共振成像的结果（使用SPM 99）获得的重复任务，在正常人与两名患者Broca和Wernicke的失语症接受言语治疗，并显示完全恢复。这两个失语症患者与左半球的损害谁表现出完全恢复表现出激活只有在右半球的代偿区在重复任务。Broca失语症的恢复涉及颞极外区与上级颞回、壳核和额下回的前上级颞区之间的重组和神经调节，而Wernicke失语症的恢复涉及颞区的上级颞回、顶叶区的后缘上回和顶下小叶之间的重组和神经调节。
We compared fMRI findings (using SPM99) obtained with repetition task in normal subjects with those of two patients with Broca's and Wernicke's aphasia who received speech therapy and showed complete recovery. Both aphasic patients with left hemisphere damage who showed complete recovery exhibited activation of only the compensatory area in the right hemisphere during the repetition task. Recovery from Broca's aphasia involves reorganization and neuromodulation between the external temporopolar area and the anterior superior temporal area of the superior temporal gyrus, putamen and the inferior frontal gyrus, while that from Wernicke's aphasia involves reorganization and neuromodulation between the superior temporal gyrus of the temporal region, the posterior supramarginal gyrus and inferior parietal lobule of the parietal region.