Checkpoints Take the Next Step
Checkpoints Take the Next Step
复制标题
检查站采取下一步行动
DOI:
10.1126/science.271.5247.314
复制
发表时间:
1996
期刊:
影响因子:
56.9
通讯作者:
A. Carr
中科院分区:
文献类型:
--
作者:
A. Carr
Checkpoints are times during the cell cycle when the cell can choose to pause if something is amiss—if its DNA is damaged or if there is a mistake in the synthesis of the new DNA—so that the damage can be repaired. The proteins of these pathways have been defined genetically. Now Carr discusses new biochemical evidence from yeast, presented in two papers in this week's issue of Science (pp. 353 and p. 357), that start to elucidate the functions of two of these proteins—Chk1 and Rad3.
影响因子:
56.9
作者:
SAVITSKY, K;BARSHIRA, A;SHILOH, Y
通讯作者:
SHILOH, Y