Causes of Death Associated With Prolonged TV Viewing: NIH-AARP Diet and Health Study.
Causes of Death Associated With Prolonged TV Viewing: NIH-AARP Diet and Health Study.
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DOI：
10.1016/j.amepre.2015.05.023
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发表时间：
2015-12
影响因子：
5.5
通讯作者：
Matthews CE
中科院分区：
文献类型：
--
作者：
Keadle SK;Moore SC;Sampson JN;Xiao Q;Albanes D;Matthews CE
看电视是最普遍的久坐行为，与心血管疾病和癌症死亡率的风险增加有关，但与其他主要死亡原因的联系尚不清楚。这项研究调查了看电视与美国主要死因之间的关系。这项研究纳入了221,426人(57%为男性)，他们年龄在50-71岁之间，在基线(1995-1996年)时没有慢性病，93%是白人，平均BMI为26.7(SD=4.4)kg/m2。参与者在基线时自我报告观看电视的情况，并被跟踪调查，直到死亡或2011年12月31日。用COX比例风险回归估计看电视的危险比(HRs)和95%的CI和死因相关死亡率。分析是在2014-2015年进行的。平均随访14.1年后，每天看电视增加2小时的调整死亡风险显著高于下列死因(HR[95%CI])：癌症(1.07[1.03，1.11])；心脏病(1.23[1.17，1.29])；慢性阻塞性肺疾病(1.28[1.14，1.43])；糖尿病(1.56[1.33，1.83])；流感/肺炎(1.24[1.02，1.50])；帕金森病(1.35[1.11，1.65])；肝病(1.33[1.05，1.67])；自杀(1.43[1.10，1.85])。死亡率协会坚持对重要的潜在混杂因素进行分层分析，减少了对因果关系的担忧。这项研究显示了与长时间看电视有关的死亡结果的广度，并确定了几种主要死亡原因的新关联。看电视是一种普遍的可自由支配的行为，可能是公共卫生干预的一个比之前认识到的更重要的目标。ClinicalTrials.gov编号，NCT00340015
TV viewing is the most prevalent sedentary behavior and is associated with increased risk of cardiovascular disease and cancer mortality, but the association with other leading causes of death is unknown. This study examined the association between TV viewing and leading causes of death in the U.S. A prospective cohort of 221,426 individuals (57% male) aged 50–71 years who were free of chronic disease at baseline (1995–1996), 93% white, with an average BMI of 26.7 (SD=4.4) kg/m2 were included. Participants self-reported TV viewing at baseline and were followed until death or December 31, 2011. Hazard ratios (HRs) and 95% CIs for TV viewing and cause-specific mortality were estimated using Cox proportional hazards regression. Analyses were conducted in 2014–2015. After an average follow-up of 14.1 years, adjusted mortality risk for a 2-hour/day increase in TV viewing was significantly higher for the following causes of death (HR [95% CI]): cancer (1.07 [1.03, 1.11); heart disease (1.23 [1.17, 1.29]); chronic obstructive pulmonary disease (1.28 [1.14, 1.43]); diabetes (1.56 [1.33, 1.83]); influenza/pneumonia (1.24 [1.02, 1.50]); Parkinson disease (1.35 [1.11, 1.65]); liver disease (1.33 [1.05, 1.67]); and suicide (1.43 [1.10, 1.85]. Mortality associations persisted in stratified analyses with important potential confounders, reducing causation concerns. This study shows the breadth of mortality outcomes associated with prolonged TV viewing, and identifies novel associations for several leading causes of death. TV viewing is a prevalent discretionary behavior that may be a more important target for public health intervention than previously recognized. ClinicalTrials.gov number, NCT00340015