EFFECT OF HIND-LIMB IMMOBILIZATION ON CONTRACTILE AND HISTOCHEMICAL PROPERTIES OF SKELETAL-MUSCLE
EFFECT OF HIND-LIMB IMMOBILIZATION ON CONTRACTILE AND HISTOCHEMICAL PROPERTIES OF SKELETAL-MUSCLE
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DOI：
10.1007/bf00591371
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发表时间：
1973-01-01
影响因子：
4.5
通讯作者：
KELSO, JR
中科院分区：
文献类型：
--
作者：
BOOTH, FW;KELSO, JR
将雄性大鼠的双后肢固定在石膏中。4周后，对后肢肌肉的连续切片进行肌球蛋白ATP酶和NADH-黄递酶染色。从固定的肢体比目鱼肌有显着较少的肌纤维比对照比目鱼肌。此外，从固定的肢体比目鱼肌有一个显着较低的百分比和较低的肌球蛋白ATP酶活性的纤维比对照组大鼠的比目鱼肌。固定也导致比目鱼肌的收缩速度明显快于对照组大鼠的比目鱼肌。有没有显着差异的收缩性能或肌球蛋白ATP酶的纤维的百分比之间的股直肌固定和控制肢体。固定肢体的股直肌深部具有高NADH-黄递酶活性的肌纤维的百分比显著小于对照组大鼠的股直肌。
Both hind limbs of male rats were immobilized in casts. After 4 weeks, serial sections of hind limb muscles were stained for myosin ATPase and NADH-diaphorase. The soleus from immobilized limbs had significantly fewer muscle fibers than the control soleus. Moreover, the soleus from immobilized limbs had a significantly lower percentage and lower number of fibers with low myosin ATPase activity than the soleus from control rats. Immobilization also resulted in the speed of contraction for the soleus being significantly faster than the soleus from control rats. There were no significant differences in the contractile properties or in the percentages of fibers with low myosin ATPase between rectus femoris muscles from immobilized and control limbs. The deep portion of the rectus femoris from immobilized limbs had a significantly smaller percentage of muscle fibers with high NADH-diaphorase activity than did the rectus femoris from control rats.