Intracavity hyperthermia in nasopharyngeal cancer: A phase III clinical study

Intracavity hyperthermia in nasopharyngeal cancer: A phase III clinical study
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DOI:
10.3109/02656736.2010.503982
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发表时间:
2011-01-01
影响因子:
3.1
通讯作者:
Piao, Yongfeng
Piao, Yongfeng
中科院分区:
医学2区
文献类型:
--
作者:
Hua, Yonghong;Ma, Shenglin;Piao, Yongfeng

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方法和材料:将未经治疗的鼻咽癌患者随机分为常规放疗组和热疗组。除治疗性放疗外,热疗组在放疗前或放疗后行腔内热疗;T90为42.5-43摄氏度,每周2次,每次50min,共7周。结果:2001年8月至2006年7月,180例符合条件的鼻咽癌患者进入本研究。两组完全缓解率(CR)分别为95.6%和81.1%(P=0.003
Methods and materials: Previously untreated NPC patients were assigned randomly into the conventional RT group and the hyperthermia group. In addition to curative RT, hyperthermia group patients received intracavity hyperthermia before or after RT; T90 was 42.5 degrees A degrees--43 degrees A degrees C for 50 min twice a week for 7 weeks.Results: From August 2001 to July 2006, 180 eligible patients with NPC were enrolled in this study. The complete response (CR) rate in the two arms (RT plus hyperthermia versus conventional RT) was 95.6%% and 81.1%%, respectively (p == 0.003, chi chi