Gene expression profiles for a prognostic immunoscore in gastric cancer.

Gene expression profiles for a prognostic immunoscore in gastric cancer.
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胃癌预后免疫评分的基因表达谱

DOI:
10.1002/bjs.10871
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发表时间:
2018-09
期刊:
The British journal of surgery
影响因子:
--
通讯作者:
Liao W
Liao W
中科院分区:
其他
文献类型:
--
作者:
Zeng D;Zhou R;Yu Y;Luo Y;Zhang J;Sun H;Bin J;Liao Y;Rao J;Zhang Y;Liao W

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越来越多的证据表明胃癌的免疫浸润与临床结果之间存在关联。然而,基于对大量肿瘤转录组推断的免疫景观的系统评估,尚未建立可靠的预后特征。目的是根据从大量肿瘤转录组推断的免疫浸润的细胞组成来开发免疫特征,以改善胃癌的预后预测。
Increasing evidence has indicated an association between immune infiltration in gastric cancer and clinical outcome. However, reliable prognostic signatures, based on systematic assessments of the immune landscape inferred from bulk tumour transcriptomes, have not been established. The aim was to develop an immune signature, based on the cellular composition of the immune infiltrate inferred from bulk tumour transcriptomes, to improve the prognostic predictions of gastric cancer.
乳腺癌中免疫浸润及其临床意义的模式:一项基于基因表达的回顾性研究。
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