Botulinum Toxin A Treatment of Perioral Rhytides
Botulinum Toxin A Treatment of Perioral Rhytides
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A型肉毒毒素治疗口周皱纹
DOI：
10.1046/j.1524-4725.2003.29118.x
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发表时间：
2003
影响因子：
2.4
通讯作者：
R. Sengelmann
中科院分区：
文献类型：
--
作者：
Natalie Semchyshyn;R. Sengelmann
背景植物毒素A作为平滑上面部的动态面部皱纹的有用疗法被充分证明。大多数对照研究都集中在眉间皱眉纹，额头水平纹和鱼尾纹的治疗上。关于肉毒杆菌毒素A用于下面部的报道很少，而且是轶事。目的：我们介绍了我们的经验，使用肉毒杆菌毒素A在嘴唇作为治疗垂直口周皱纹，这导致了额外的美容效益，唇外翻和增强唇丰满。方法对18例垂直型唇裂患者进行A型肉毒毒素注射。术后2 ~ 3周评价治疗效果。结果：口周注射A型肉毒毒素治疗的患者中，观察到功能亢进的线条和上唇丰满/外翻变平滑; 72%的患者继续治疗。结论：在选定的患者中，口周肉毒毒素A可改善口周皱纹，增强唇部丰满度和唇部外翻。
BACKGROUND Botulinum toxin A is well documented as a useful therapy for smoothing dynamic facial rhytides of the upper face. Most controlled studies have focused on the treatment of glabellar frown lines, horizontal forehead lines, and crow's feet. Reports of botulinum toxin A use in the lower face are few and anecdotal. OBJECTIVE We present our experience using botulinum toxin A in the lip as a treatment of vertical perioral rhytides, which resulted in the added cosmetic benefits of lip eversion and enhanced lip fullness. METHODS Eighteen patients were injected with botulinum toxin A into the vertical lip rhytides. The effect of treatment was evaluated at 2 to 3 weeks after procedure. RESULTS Smoothening of hyperfunctional lines and upper lip fullness/eversion is observed in patients treated with perioral botulinum toxin A injections; 72% of patients continued treatment. CONCLUSIONS In select patients, perioral botulinum toxin A results in amelioration of perioral rhytides and enhancement of lip fullness and lip eversion.