Is there any correlation between the ATS, BTS, ERS and GOLD COPD's severity scales and the frequency of hospital admissions?
Is there any correlation between the ATS, BTS, ERS and GOLD COPD's severity scales and the frequency of hospital admissions?
复制标题
ATS、BTS、ERS 和 GOLD COPD 严重程度与入院频率之间是否存在相关性？
DOI：
10.1016/j.rmed.2003.09.011
复制
发表时间：
2004
影响因子：
4.3
通讯作者：
N. Siafakas
中科院分区：
文献类型：
--
作者：
M. Tsoumakidou;N. Tzanakis;Olga Voulgaraki;I. Mitrouska;Georgios Chrysofakis;M. Samiou;N. Siafakas
考虑到疾病严重程度的分类，不同的慢性阻塞性肺病指南之间存在分歧。我们研究的目的是确定各种 COPD 指南（ATS、BTS、ERS 和 GOLD）的严重程度与 COPD 恶化住院频率之间是否存在相关性。从克里特岛伊拉克利翁大学医院肺部诊所收治急性加重的患者中招募了 67 名 COPD 患者（65 名男性 - 2 名女性，45 名戒烟者，22 名当前吸烟者，年龄（69.4±1.1））。出院后 2 个月的定期访视时，在病情稳定的情况下进行了肺功能测试和动脉血气分析。根据 ATS、BTS、ERS 和 GOLD 严重程度等级，使用本次就诊的 FEV1 百分比预测测量将患者分为轻度、中度和重度。记录接下来 18 个月内因急性加重住院的人数。总共记录了 165 次恶化。使用 GOLD 严重程度分类系统，COPD 严重程度与每年住院次数之间的相关性具有统计学意义（P=0.02 和 r=0.294）。住院人数与 ERS 分类系统之间也存在弱相关性（P=0.05，r=0.24）。住院人数与 ATS 或 BTS 严重程度量表之间没有发现统计学上显着的相关性。总之，COPD 严重程度的 GOLD 和 ERS 分类系统与导致住院的病情恶化相关。 ATS 和 BTS 严重程度量表的情况并非如此。与 GOLD 量表取得了更好的相关性。
Disagreement exists between different COPD guidelines considering classification of severity of the disease. The aim of our study was to determine whether there is any correlation between severity scales of various COPD guidelines (ATS, BTS, ERS and GOLD) and the frequency of hospitalisations for COPD exacerbation. A cohort of 67 COPD patients (65 male–2 female, 45 ex-smokers, 22 current smokers, aged (69.4±1.1)) was recruited from those admitted in the pulmonary clinic of the University Hospital of Heraklion, Crete for an acute exacerbation. Lung function tests and arterial blood gases analyses were performed during stable conditions at a scheduled visit 2 months after discharge. The patients were stratified using the FEV1percent-predicted measurement of this visit into mild, moderate and severe in accordance to the ATS, BTS, ERS and GOLD scales of severity. The number of hospitalisations for acute exacerbation was recorded for the following 18 months. A total of 165 exacerbations were recorded. The correlation between the severity of COPD and the number of hospitalisations per year was statistically significant using the GOLD classification system of severity (P=0.02 and r=0.294). A weak correlation was also found between the number of hospitalisations and the ERS classification system (P=0.05 and r=0.24). No statistically significant correlation was found between the number of hospitalisations and the ATS or BTS severity scales. In conclusion the GOLD and ERS classification systems of severity of COPD correlated to exacerbations causing hospitalisation. The same was not true for the ATS and BTS severity scales. Better correlation was achieved with the GOLD scale.