Association of Gestational Diabetes Mellitus and Perinatal Maternal Depression with Early Childhood Behavioral Problems: An Environmental Influences on Child Health Outcomes (ECHO) Study.
Association of Gestational Diabetes Mellitus and Perinatal Maternal Depression with Early Childhood Behavioral Problems: An Environmental Influences on Child Health Outcomes (ECHO) Study.
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妊娠糖尿病和围产期母亲抑郁与幼儿行为问题的关联：环境对儿童健康结果的影响 (ECHO) 研究。
DOI：
10.1111/cdev.13938
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发表时间：
2023
影响因子：
4.6
通讯作者：
Hockett,C
中科院分区：
文献类型：
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作者：
Shuffrey,LaurenC;Morales,Santiago;Jacobson,MelanieH;BosquetEnlow,Michelle;Ghassabian,Akhgar;Margolis,AmyE;Lucchini,Maristella;Carroll,KeciaN;Crum,RosaM;Dabelea,Dana;Deutsch,Arielle;Fifer,WilliamP;Goldson,Brandon;Hockett,C
本研究对2379名年龄为4.12 ± 0.60岁的儿童进行了学龄前儿童行为检查表（Preschool Child Behavior Checklist）上的外化、内化和自闭症谱系问题与妊娠期糖尿病（GDM）、产前和产后母亲抑郁症状的相关性研究（48%为女性; 47%为白色，32%为黑人，15%为混血儿，4%为亚洲人，<2%为美洲印第安人/阿拉斯加土著人，<2%为夏威夷土著人; 23%为西班牙裔）。数据收集自2009 - 2021年NIH环境对儿童健康结果的影响（ECHO）计划。妊娠期糖尿病，产前和产后的母亲抑郁症状与增加儿童外化和内化的问题。GDM与孤独症行为增加仅在暴露于高于中位数水平的围产期母亲抑郁症状的儿童中相关。分层分析显示，GDM和儿童结局之间的关系，只有男性。
This study examined the association of gestational diabetes mellitus (GDM), prenatal, and postnatal maternal depressive symptoms with externalizing, internalizing, and autism spectrum problems on the Preschool Child Behavior Checklist in 2379 children aged 4.12 ± 0.60 (48% female; 47% White, 32% Black, 15% Mixed Race, 4% Asian, <2% American Indian/Alaskan Native, <2% Native Hawaiian; 23% Hispanic). Data were collected from the NIH Environmental influences on Child Health Outcomes (ECHO) Program from 2009‐2021. GDM, prenatal, and postnatal maternal depressive symptoms were each associated with increased child externalizing and internalizing problems. GDM was associated with increased autism behaviors only among children exposed to perinatal maternal depressive symptoms above the median level. Stratified analyses revealed a relation between GDM and child outcomes in males only.