Biological and historical overview of Zika virus.
Biological and historical overview of Zika virus.
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DOI：
10.5501/wjv.v6.i1.1
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发表时间：
2017-02-12
期刊：
影响因子：
--
通讯作者：
Tang Q
中科院分区：
文献类型：
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作者：
Armstrong N;Hou W;Tang Q
最近寨卡病毒的爆发引起了全世界的关注，可能是因为最近受影响的国家（巴西）将举办2016年奥运会。寨卡病毒感染病例现在正在蔓延到许多其他国家，其感染可能与一些严重的医学后遗症有关。自1947年在乌干达首次将其与受感染的猴子分离以来，直到最近爆发之前，只进行了几项研究。从文献文献的历史来看，1989年到2007年有19年的差距。这可能是因为从感染寨卡病毒的人群中只诊断出轻微的疾病。显然，最近关于寨卡病毒感染可能与新生儿小头畸形有关的报道使我们重新评估病毒病原体的医学意义。它可以通过性行为或蚊虫叮咬传播。寨卡病毒的性传播使其与黄病毒属的其他成员区别开来。通过全面调查，包括基础研究、流行研究、亚临床研究和临床研究，需要获得寨卡病毒的详细信息。在此，我们回顾了寨卡病毒的已发表信息。
The recent outbreak of the Zika virus attracts worldwide attention probably because the most recently affected country (Brazil) will host the 2016 Olympic Game. Zika virus infected cases are now spreading to many other countries and its infection might be linked to some severe medical sequelae. Since its first isolation from the infected monkey in 1947 in Uganda, only a few studies had been taken until recent outbreak. According to the history of referenced publications, there is a 19-year gap from 1989 to 2007. This might be because only mild diseases were diagnosed from Zika virus infected populations. Obviously, the recent reports that Zika virus infection is probably associated with microcephaly of the neonates makes us reevaluate the medical significance of the viral pathogen. It can be transmitted sexually or by mosquito biting. Sexual transmission of the Zika virus distinguishes it from other members of the Genus Flavivirus. Detailed information of the Zika virus is needed through a thorough investigation covering basic, epidemical, subclinical and clinical studies. Here, we reviewed the published information of Zika virus.