Commentary: the quest for women's prophylactic methods--hopes vs science.
Commentary: the quest for women's prophylactic methods--hopes vs science.
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评论：对女性预防方法的探索——希望与科学。
DOI：
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发表时间：
1992
影响因子：
12.7
通讯作者：
J. Trussell
中科院分区：
文献类型：
--
作者：
W. Cates;F. Stewart;J. Trussell
Rosenberg和Gollub在本期的配套文章总结了来自10项观察性研究的数据，并得出结论，在典型条件下，女性控制的避孕方法在预防性传播疾病方面与避孕套相当，应该这样销售。虽然我们同意化学和机械避孕药可以预防一些性传播疾病，但我们认为作者夸大了这些方法的科学依据，特别是与避孕套相比。我们认为，关于杀精剂对人体免疫缺陷病毒的绝对保护作用及其相对于避孕套对其他性传播疾病的保护程度，目前的数据仍然没有定论。三个原因解释了我们的差异：比较数据的局限性;杀精剂对阴道状况的不良影响，包括生殖器溃疡;以及避孕套的相对价值，即使在典型的条件下，在预防性传播疾病。出于这些原因，我们目前会建议进行高风险性行为的女性和男性使用安全套作为他们的第一道防线。如果这是不可接受的，女性屏障成为一个后备阵地，以防止细菌性性传播疾病。
The companion article by Rosenberg and Gollub in this issue summarizes data from 10 observational studies and concludes that female-controlled contraceptive methods, under typical conditions, are comparable to condoms in preventing sexually transmitted diseases and should be merchandized as such. While we agree that chemical and mechanical contraceptives provide protection against some sexually transmitted diseases, we think the authors have overstated the scientific case for these methods, especially in comparison with the condom. We think the current data remain inconclusive regarding the absolute protection of spermicides against the human immunodeficiency virus and their level of protection--relative to that of the condom--against other sexually transmitted diseases. Three reasons account for our differences: the limitations in the comparative data; the reported adverse effects of spermicides on vaginal conditions, including genital ulcers; and the relative value of condoms, even under typical conditions, in preventing sexually transmitted diseases. For these reasons, we would currently counsel both women and men who practice high-risk sexual behaviors to use condoms as their first line of defense. If this is unacceptable, the female barriers become a fallback position to protect against bacterial sexually transmitted diseases.
评论：女性可以使用的方法来预防性传播疾病，包括艾滋病毒。
影响因子：
12.7
作者：
Rosenberg,MJ;Gollub,EL
通讯作者：
Gollub,EL