Developmental timing of child maltreatment and symptoms of depression and suicidal ideation in young adulthood: results from the National Longitudinal Study of Adolescent Health.
Developmental timing of child maltreatment and symptoms of depression and suicidal ideation in young adulthood: results from the National Longitudinal Study of Adolescent Health.
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DOI：
10.1002/da.22102
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发表时间：
2013-10
影响因子：
7.4
通讯作者：
Smoller JW
中科院分区：
文献类型：
--
作者：
Dunn EC;McLaughlin KA;Slopen N;Rosand J;Smoller JW
虐待儿童是导致精神病的潜在危险因素。虽然第一次暴露于虐待的发展时间被认为是重要的，在塑造未来的精神病理学的风险，没有共识存在是否较早或较晚的暴露更有害。本研究旨在探讨首次接触虐待的年龄是否与随后的抑郁症和自杀意念有关。数据来自国家青少年健康纵向研究（n= 15，701）。第一次遭受虐待的时间分类如下：（1）粗略测量，涵盖儿童早期（0-5）、儿童中期（6-10）或青春期（11-17）;（2）精细测量，涵盖婴儿期（0-2）、学龄前（3-5）、潜伏期（6-8）、青春期前（9-10）、青春期（11-13）或青春期（14-17）。我们研究了在整个样本和那些暴露于虐待的人中，首次暴露的时间是否与成年早期的抑郁和自杀意念有关。在任何年龄暴露于身体虐待的受访者在年轻的成年期比未受虐待的受访者有更高的抑郁症和自杀意念的几率。在受虐待的受访者中，在幼儿期（0-5岁），特别是学龄前（3-5岁）接触虐待与抑郁症的关系最为密切。与青少年时期遭受虐待的受访者相比，在学龄前首次接触身体虐待的受访者患抑郁症的几率增加了77%，而在幼儿期首次接触性虐待的受访者自杀意念的几率增加了146%。首次暴露于虐待的发育时间影响抑郁症和自杀意念的风险。这些发现是否是基于生物学的敏感期的证据，需要进一步研究。
Child maltreatment is a potent risk factor for psychopathology. Although the developmental timing of first exposure to maltreatment is considered important in shaping risk of future psychopathology, no consensus exists on whether earlier or later exposures are more deleterious. This study examines whether age at first exposure to abuse is associated with subsequent depression and suicidal ideation. Data were drawn from the National Longitudinal Study on Adolescent Health (n=15,701). Timing of first maltreatment exposure was classified using: (1) a crude measure capturing early childhood (0–5), middle childhood (6–10), or adolescence (11–17); and (2) a refined measure capturing infancy (0–2), preschool (3–5), latency (6–8), prepubertal (9–10), pubertal (11–13), or adolescence (14–17). We examined whether timing of first exposure was associated with depression and suicidal ideation in early adulthood in the entire sample and among those exposed to maltreatment. Respondents exposed to physical abuse at any age had a higher odds of depression and suicidal ideation in young adulthood than non-maltreated respondents. Among maltreated respondents, exposure during early childhood (0–5), particularly pre-school (3–5), was most strongly associated with depression. Respondents first exposed to physical abuse during preschool had a 77% increase in the odds of depression and those first exposed to sexual abuse during early childhood had a 146% increase in the odds of suicidal ideation compared to respondents maltreated as adolescents. Developmental timing of first exposure to maltreatment influences risk for depression and suicidal ideation. Whether these findings are evidence for biologically-based sensitive periods requires further study.
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影响因子：
3.3
作者：
Keiley, ML;Howe, TR;Pettit, GS
通讯作者：
Pettit, GS
影响因子：
--
作者：
McLaughlin, Katie A.;Green, Jennifer Greif;Gruber, Michael J.;Sampson, Nancy A.;Zaslavsky, Alan M.;Kessler, Ronald C.
通讯作者：
Kessler, Ronald C.
影响因子：
7.4
作者：
Dunn, Erin C.;Gilman, Stephen E.;Molnar, Beth E.
通讯作者：
Molnar, Beth E.
DOI：
10.1097/01.chi.0000181047.59702.58
发表时间：
2005-12-01
影响因子：
13.3
作者：
Lieberman, AF;Van Horn, P;Ippen, CG
通讯作者：
Ippen, CG
影响因子：
5.4
作者：
Fletcher, Jason M.
通讯作者：
Fletcher, Jason M.