The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) initiative: methods of the EGAPP Working Group

The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) initiative: methods of the EGAPP Working Group
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DOI:
10.1097/gim.0b013e318184137c
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发表时间:
2009-01-01
影响因子:
8.8
通讯作者:
Berg, Alfred O.
Berg, Alfred O.
中科院分区:
医学1区
文献类型:
--
作者:
Teutsch, Steven M.;Bradley, Linda A.;Berg, Alfred O.

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由疾病控制和预防中心的国家公共卫生基因组学办公室建立的基因组应用实践和预防评估(EGAPP)倡议支持制定和实施严格的循证流程,以评估美国临床和公共卫生实践中的基因检测和其他基因组应用。一个独立的,非联邦的EGAPP工作。EWG是一个多学科专家小组,负责选择主题,监督证据的系统性审查,并根据证据提出建议。本文介绍了EGAPP流程,并详细介绍了EWG使用的具体方法和途径。
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative, established by the National Office of Public Health Genomics at the Centers for Disease Control and Prevention, supports the development and implementation of a rigorous, evidence-based process for evaluating genetic tests and other genomic applications for clinical and public health practice in the United States. An independent, non-federal EGAPP Working. Group (EWG), a multidisciplinary expert panel selects topics, oversees the systematic review of evidence, and makes recommendations based on that evidence. This article describes the EGAPP processes and details the specific methods and approaches used by the EWG.