Gastric slow wave abnormalities in patients with gastroparesis.
Gastric slow wave abnormalities in patients with gastroparesis.
复制标题
胃轻瘫患者的胃慢波异常。
DOI：
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发表时间：
1992
影响因子：
9.8
通讯作者：
R. McCallum
中科院分区：
文献类型：
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作者：
Jiande D. Z. Chen;R. McCallum
本研究的目的是确定皮肤胃电图（EGGs）是否可以用来区分胃轻瘫患者无症状的健康对照。从24名无症状健康志愿者和27名胃轻瘫患者中获得餐前和餐后皮肤EGG，这些患者通过固体试验餐的胃排空延迟来记录。介绍了慢波异常的定义。对于空腹状态，所有2 - 4例对照组均显示出高度规则的主峰，范围为2-4个周期/分钟（cpm），而患者组中有11例受试者显示出不存在正常的慢波活动（p <0.001）。对于餐后条件，再次，所有2 - 4个对照组显示慢波正常性，包括2-4 cpm频率分量的振幅和规律性增加。这与患者组形成鲜明对比，其中13例受试者显示异常（p <0.0001）。大约75%的患者有异常的餐前或餐后EGG：4例患者在空腹和进食后都有异常的EGG，7例患者在空腹时有异常的EGG，但进食后正常，9例患者在空腹时有正常的EGG，但进食后异常。我们的结论是，皮肤胃电图可用于区分胃轻瘫患者无症状的正常人。
The aim of this study was to determine whether cutaneous electrogastrograms (EGGs) could be used to differentiate gastroparetic patients from asymptomatic healthy controls. Pre- and postprandial cutaneous EGGs were obtained from 24 asymptomatic healthy volunteers and 27 patients with gastroparesis documented by a delayed gastric emptying of a solid test meal. A definition of slow wave abnormality was introduced. For the fasted condition, all 24 controls showed highly regular, predominant peaks in the 2-4 cycles/min (cpm) range, in contrast to the patient group in which 11 subjects showed an absence of normal slow wave activity (p less than 0.001). For the postprandial condition, again, all 24 controls showed slow wave normality consisting of increased amplitude and regularity of the 2-4 cpm frequency component. This was in sharp contrast to the patient group in which 13 subjects showed abnormalities (p less than 0.0001). Approximately 75% of the patients had an abnormal pre- or postprandial EGG: four patients had abnormal EGGs both during fasting and after eating, seven patients had abnormal EGGs during fasting but normal EGGs after eating, and nine patients had normal EGGs during fasting but abnormal EGGs after eating. We conclude that the cutaneous EGG may be used to differentiate gastroparetic patients from asymptomatic normals.