Three-dimensional morphology of the human embryonic brain.
Three-dimensional morphology of the human embryonic brain.
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DOI：
10.1016/j.dib.2015.05.001
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发表时间：
2015-09
期刊：
影响因子：
1.2
通讯作者：
Takakuwa T
中科院分区：
文献类型：
--
作者：
Shiraishi N;Katayama A;Nakashima T;Yamada S;Uwabe C;Kose K;Takakuwa T
利用来自京都收藏的卡内基13期至23期人类胚胎标本的图像，在3D电影中可视化了脑泡和脑室的形态发生。这些图像是用配备2.35-T超导磁体的磁共振显微镜获得的。使用相同比例的三维图像有效地展示了大脑的发育和生长。利用基于厚度的表面颜色映射显示脑组织厚度的不均匀，这可能表明大脑的分化。对菱形脑的独特而复杂的分化，特别是对脑组织的内部视图和增厚进行了更近距离的观察。目前的数据有助于更好地理解大脑和脑室的发育。
The morphogenesis of the cerebral vesicles and ventricles was visualized in 3D movies using images derived from human embryo specimens between Carnegie stage 13 and 23 from the Kyoto Collection. These images were acquired with a magnetic resonance microscope equipped with a 2.35-T superconducting magnet. Three-dimensional images using the same scale demonstrated brain development and growth effectively. The non-uniform thickness of the brain tissue, which may indicate brain differentiation, was visualized with thickness-based surface color mapping. A closer view was obtained of the unique and complicated differentiation of the rhombencephalon, especially with regard to the internal view and thickening of the brain tissue. The present data contribute to a better understanding of brain and cerebral ventricle development.