Applications of PLA in modern medicine
Applications of PLA in modern medicine
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DOI：
10.1016/j.engreg.2020.08.002
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发表时间：
2020-09-06
影响因子：
--
通讯作者：
Tabada A
中科院分区：
文献类型：
--
作者：
DeStefano V;Khan S;Tabada A
聚乳酸（PLA）是一种多用途的生物聚合物。聚乳酸是由丰富的可再生资源合成的，易于生物降解。PLA作为一种生物材料在大量的医疗保健应用中显示出前景，如组织工程或再生医学、心血管植入物、牙科龛、药物载体、骨科干预、癌症治疗、皮肤和肌腱愈合，以及最后的医疗工具/设备。PLA作为一种三维（3D）可打印的生物聚合物已经证明了它的重要性，在2019年冠状病毒病（Covid-19）全球大流行期间，它的作用进一步得到了支持。作为一种丰富的材料，PLA已经制造出了急需的个人防护装备（PPE）和呼吸机改装。随着聚合物化学的不断发展，基于pla的模态的应用和持续的有效性也将不断提高。
Polylactic acid (PLA) is a versatile biopolymer. PLA is synthesized with ease from abundant renewable resources and is biodegradable. PLA has shown promise as a biomaterial in a plethora of healthcare applications such as tissue engineering or regenerative medicine, cardiovascular implants, dental niches, drug carriers, orthopedic interventions, cancer therapy, skin and tendon healing, and lastly medical tools / equipment. PLA has demonstrated instrumental importance as a three-dimensionally (3D) printable biopolymer, which has further been bolstered by its role during the Coronavirus Disease of 2019 (Covid-19) global pandemic. As an abundant filament, PLA has created desperately needed personal protective equipment (PPE) and ventilator modifications. As polymer chemistry continues to advance, so too will the applications and continued efficacy of PLA-based modalities.