Visceral adiposity index as a useful tool for the assessment of cardiometabolic disease risk in women aged 65 to 74
Visceral adiposity index as a useful tool for the assessment of cardiometabolic disease risk in women aged 65 to 74
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DOI：
10.1002/dmrr.3052
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发表时间：
2018-11-01
影响因子：
8
通讯作者：
Dabrowski, Mariusz
中科院分区：
文献类型：
--
作者：
Derezinski, Tadeusz;Zozulinska-Ziolkiewicz, Dorota;Dabrowski, Mariusz
内脏肥胖指数（VAI）被认为是脂肪组织功能障碍和心脏代谢疾病风险的可靠指标。本研究的目的是评估其在评估心脏代谢风险的样本中的老年妇女生活在农村和城市社区在波兰中部的有用性。方法结果共有365名年龄在65岁至74岁之间的女性参与了这项横断面研究。所有患者均接受了访谈，以获得他们的糖尿病，心肌梗死，中风和血运重建的历史。对所有参与者进行人体测量，然后计算体重指数（BMI）和腰/臀比。测量手臂和双踝的血压，并计算踝/臂指数。采集血液样本用于评估血脂、血脂和肌酐水平。在空腹血糖升高的患者中，重复该试验，或在适当时进行口服葡萄糖耐量试验。最后，测量所有女性的颈动脉内膜中层厚度。参与者的VAI与心肌梗死史、颈动脉内膜中层厚度增加、糖尿病、糖尿病前期和肾功能受损显著相关。此外，VAI与这些终点的相关性优于BMI或腰围。结论VAI可被认为是评估老年女性心脏代谢疾病风险的有用工具，评分≥ 2.71代表了识别高危女性的截断点。在这些患者中，筛查心血管疾病、糖代谢异常和肾功能受损应成为常规做法。
Background The visceral adiposity index (VAI) is considered to be a reliable indicator of adipose tissue dysfunction and cardiometabolic disease risk. The aim of this study was to evaluate its usefulness in assessing cardiometabolic risk in a sample of elderly women living in a rural-urban community in central Poland. Methods Results A total of 365 women aged 65 to 74 years were included in this cross-sectional study. All patients were interviewed to obtain their history of diabetes mellitus, myocardial infarction, stroke, and revascularization. For all participants, anthropometric measurements were performed, then body mass index (BMI) and waist/hip ratio were calculated. Blood pressure was measured on the arm and on both ankles, and the ankle/brachial index was calculated. Blood samples were collected for the assessment of glycemia, lipid profile, and creatinine level. In patients with elevated fasting glucose, the test was repeated, or an oral glucose tolerance test was performed where appropriate. Finally, carotid intima-media thickness was measured in all women. The VAI of participants was significantly correlated with a history of myocardial infarction, higher carotid intima-media thickness, diabetes, prediabetes, and impaired kidney function. Furthermore, VAI demonstrated a better correlation with these endpoints than BMI or waist circumference. Conclusions The VAI can be considered a useful tool for the assessment of cardiometabolic disease risk in elderly women, with a score of >= 2.71 representing the cut-off point for identifying females at high risk. In such patients, screening for cardiovascular disease, abnormal glucose metabolism, and impaired kidney function should be routine practice.