Antibiotic resistance: the pros and cons of probiotics.
Antibiotic resistance: the pros and cons of probiotics.
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DOI：
10.1016/s1590-8658(07)60006-1
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发表时间：
2006-12-01
期刊：
影响因子：
--
通讯作者：
Courvalin, Patrice
中科院分区：
文献类型：
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作者：
Courvalin, Patrice
为了预防肠道疾病，可以使益生菌在共同施用的抗生素存在下具有多药耐药性以存活。这产生了从益生菌直接或间接通过肠道植物群向人类细菌病原体转移抗性的可能性。本文综述了抗生素耐药益生菌安全性评价的实验方法和评价标准。
For the prevention of intestinal disorders, probiotics can be rendered multidrug resistant to survive in the presence of co-administered antibiotics. This generates the possibility of resistance transfer from the probiotic to human bacterial pathogens, either directly or indirectly via the commensal flora. This article reviews the experiments to be performed and the criteria for assessment of safety of antibiotic resistant probiotics.