Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis.
Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis.
复制标题
含蝎子的中药复方治疗癫痫：系统评价和荟萃分析方案。
DOI：
10.1097/md.0000000000025134
复制
发表时间：
2021-03-12
期刊：
影响因子：
1.6
通讯作者：
Ma R
中科院分区：
文献类型：
--
作者：
Rong P;Fu Q;Zhang X;Liu X;Yang J;Wang X;Wang S;Liu H;Ma R;Nie L;Ma R
癫痫是常见的神经发育性疾病之一。它可以影响约0.5%至1.0%的人口，无论他们的种族和社会阶层。尽管开发了广泛的治疗方法，但仍有约三分之一的患者仍然会出现癫痫发作。含蝎中药复方对神经保护和癫痫有显著疗效。但目前还没有研究评估其临床疗效和安全性。检索相关中英文数据库中有关CHCCS治疗癫痫的各项数据。主要结局是CHCCS对癫痫的疗效。次要结局包括复发率和副作用。将评估偏倚风险，并将使用RevMan5.3和Stata14.0进行荟萃分析。最后，我们将评估所产生的证据的水平。研究结果将与现有证据相结合，并发表在同行评审期刊上。本研究将专门研究CHCCS治疗癫痫的有效性和安全性。INPLASY202120056。
Epilepsy is 1 of the common neurodevelopmental diseases. It can affect about 0.5% to 1.0% of the population regardless of their race and social class. Despite the development of a wide range of treatments, there remaining about one-third of patients still experience seizures. Chinese herbal compounds containing scorpion (CHCCS) have shown an outstanding curative effect on nerve protection and epilepsy. But there's no study to assess its clinical efficacy and safety. Each data of CHCCS in treating epilepsy from related English and Chinese databases will be searched. The primary outcome is the efficacy of the CHCCS on epilepsy. And the secondary outcomes include recurrence rate and side effects. The risk of bias will be assessed, and RevMan5.3 and Stata14.0 will be performed for meta-analysis. Finally, we will assess the level of the resulting evidence. The results of the study will be combined with current evidence and published in a peer-reviewed journal. This study will specifically investigate the effectiveness and safety of CHCCS in treating epilepsy. INPLASY202120056.