THREE CASES OF MALIGNANT CHANGE IN ENDOMETRIOSIS, INCLUDING TWO CASES ARISING IN THE RECTO‐VAGINAL SEPTUM
THREE CASES OF MALIGNANT CHANGE IN ENDOMETRIOSIS, INCLUDING TWO CASES ARISING IN THE RECTO‐VAGINAL SEPTUM
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子宫内膜异位症恶变三例，其中两例发生于直肠阴道隔膜
DOI：
10.1111/j.1471-0528.1958.tb06204.x
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发表时间：
1958
期刊：
影响因子：
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通讯作者：
S. G. Clayton
中科院分区：
文献类型：
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作者：
H. P. Ferreira;S. G. Clayton
自1925年Sampson报道7例可见邻近子宫内膜组织的卵巢癌以来，许多文献讨论了卵巢子宫内膜异位症恶变的可能性。在其中4例中，他认为癌是良性子宫内膜囊肿的继发性变化。确定癌是以这种方式产生的困难是众所周知的，随后的作者更加挑剔;例如，诺瓦克（1947）认为只有一个桑普森的病例是可以接受的。为了确定乳腺癌中出现了恶性生长，可能需要以下标准：（1）恶性肿瘤必须与乳腺癌有直接关系，最好是乳腺癌和癌之间的直接过渡。(2)不应有其他明显的恶性病变原发部位。(3)恶性肿瘤的组织学表现应使其来源于腺瘤成为可能。下面的列表包括了大多数卵巢上皮性腺瘤发生癌的病例，这些病例的起源证据是可以接受的，尽管还有许多其他不太令人信服的报道：Sampson（1925），7例中描述了1例; Teilum（1945）; McCullough et at.（1946）; Kuzuma（1947），描述了2例中的1例; 6例P1。[41] Novak（1947）; Rauramo（1947）;米勒等.（1947年）; Moss和Runals（1948）; Corner等（1950），描述了6例中的2例; Bacher和Hertzog（1951）; Scott（1953）; Hunter和Klein（1954），描述了2例中的1例; Postoloff和Rodenberg（1955）; Weinrod等（1956）;格林和Enterline（1957），描述了2例中的1例。16例中腺癌10例，腺棘皮瘤型和表皮样型10例。Thompson（1957）最近报道了16例原发性卵巢腺棘皮瘤，其中12例与子宫内膜异位症有关。在7例病例中，腺棘皮瘤实际上可以看到出现在子宫内膜异位症的区域，因此这7例病例可以添加到上述列表中。很可能许多其他外科医生遇到过卵巢良性肿瘤的单个病例，但没有报道过，但从文献中此类报道的罕见性来判断，这一定是一种非常罕见的癌症。因此，我们记录下以下案例。
THE possibility of malignant change in endometriosis of the ovary has been discussed in numerous papers published since 1925 when Sampson described 7 cases of ovarian carcinoma in which adjacent endometrial tissue could be seen. In 4 of these cases he suggested that the carcinoma arose as a secondary change in a benign endometrial cyst. The difficulty of establishing that a carcinoma has arisen in this way is well recognized and subsequent writers have been more critical; Novak (1947), for example, considered that only one of Sampson’s cases was acceptable. To be satisfied that a malignant growth has arisen in an endometrioma the following criteria may be necessary: (1) The malignant tumour must be in direct relationship to the endometrioma, and preferably direct transition between the endometrioma and carcinoma should be seen. (2) No other primary site of malignant disease should be evident. (3) The histological appearance of the malignant growth should be such that its origin from an endometrioma is possible. The following list includes the majority of the cases of carcinoma arising in ovarian endometrioma that have been reported and in which the evidence for this origin is acceptable, although many other less convincing reports have been published : Sampson (1925), 1 case out of 7 described; Teilum (1945); McCullough et at. (1946); Kuzuma (1947), 1 case out of 2 described; 6 P1. 41 Novak (1947); Rauramo (1947); Miller et at. (1947); Moss and Runals (1948); Corner et al. (1950), 2 cases out of 6 described; Bacher and Hertzog (1951); Scott (1953); Hunter and Klein (1954), 1 case out of 2 described; Postoloff and Rodenberg (1955) ; Weinrod et al. (1956); Greene and Enterline (1957), 1 case out of 2 described. Ten of these 16 cases were adenocarcinomatous, and the others were adenoacanthomatous or of epidermoid type. In a recent report Thompson (1957) described 16 new cases of primary ovarian adenoacanthoma, and in 12 of these there was an association with endometriosis. In 7 cases the adenoacanthoma could actually be seen to arise in an area of endometriosis, so that these 7 cases may be added to the list above. It is likely that many other surgeons have encountered single cases of carcinoma arising in ovarian endometriomata and have not reported them, but to judge from the infrequency of such reports in the literature this must be a very rare type of cancer. For that reason we record the following case.