Attention-deficit hyperactivity disorder in adults with epilepsy

Attention-deficit hyperactivity disorder in adults with epilepsy
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DOI:
10.1016/j.yebeh.2019.106543
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发表时间:
2019-12-01
影响因子:
2.6
通讯作者:
Asadi-Pooya, Ali A.
Asadi-Pooya, Ali A.
中科院分区:
医学3区
文献类型:
--
作者:
Ashjazadeh, Nahid;Sahraeian, Ali;Asadi-Pooya, Ali A.

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目的:我们调查成人癫痫患者中注意缺陷多动障碍(ADHD)的患病率。我们假设,ADHD是常见的成人PWE和,一些临床因素可能与ADHD.Methods:在这个横断面研究中,200名成人PWE提到我们的神经科诊所在设拉子,伊朗招募(连续采样)。使用经验证的波斯语版本的成人ADHD自我报告量表(ASRS v1.1)和Addenbrooke认知检查修订版(ACE-R)测试。结果:男性82例(41%),女性118例(59%)。70例患者(35%)ADHD筛查阳性。在整个组中,认知功能与ADHD阳性筛查的患病率之间存在显着相关性; 19例(18%)认知正常的患者,23例(42%)轻度障碍患者和28例(70%)重度认知障碍患者筛查ADHD阳性(p = 0.0001)。105例患者认知功能正常,并分别进行了研究。19名患者(18%)的ADHD筛查呈阳性。注意缺陷多动障碍与任何测试变量在这些patients.Conclusion:约五分之一的成年癫痫和正常的认知功能可能有一个积极的屏幕多动症。对所有PWE进行常规筛查以早期发现和适当管理ADHD将是一种合理的方法。(C)2019 Elsevier Inc版权所有。
Purpose: We investigated the prevalence of attention-deficit hyperactivity disorder (ADHD) in adult people with epilepsy (PWE). We hypothesized that ADHD is common among adult PWE and, some clinical factors may be associated with ADHD.Methods: In this cross-sectional study, 200 adult PWE referred to our neurology clinic at Shiraz, Iran were recruited (consecutively sampled). Validated Persian versions of Adult ADHD Self-Report Scale (ASRS v1.1) and Addenbrooke's Cognitive Examination-Revised (ACE-R) tests were used. We performed univariate analyses and also a logistic regression analysis.Results: Eighty-two patients (41%) were male, and 118 (59%) were female. Seventy patients (35%) had a positive screen for ADHD. There was a significant association between cognitive function and the prevalence of positive screening for ADHD in the whole group; 19 (18%) of the patients with a normal cognition, 23 (42%) of those with mild impairment, and 28 (70%) of those with severe cognitive impairment screened positive for ADHD (p = 0.0001). One hundred and five patients had normal cognition and were studied separately. Nineteen patients (18%) had screened positive for ADHD. Attention-deficit hyperactivity disorder was not associated with any of the tested variables in these patients.Conclusion: About one-fifth of adults with epilepsy and normal cognitive function may have a positive screen for ADHD. Routine screening of all PWE for early detection and appropriate management of ADHD would be a reasonable approach. (C) 2019 Elsevier Inc All rights reserved.