Thermal ablation versus surgical resection for localized hepatocellular carcinoma: a population study using the SEER database
Thermal ablation versus surgical resection for localized hepatocellular carcinoma: a population study using the SEER database
复制标题
DOI：
10.2217/fon-2017-0447
复制
发表时间：
2018-03-01
期刊：
影响因子：
3.3
通讯作者：
Akinwande, Olaguoke
中科院分区：
文献类型：
--
作者：
Mills, Abigail;Thayer, David;Akinwande, Olaguoke
目的：使用监测、流行病学和最终结果数据库比较接受手术切除（SR）或热消融（TA）治疗的局限性肝细胞癌患者的总生存期（OS）和肝癌特异性生存期（LCSS）。材料与方法：确定患者后进行Kaplan-Meier、竞争风险和考克斯回归分析。然后应用倾向分数匹配。结果：SR组的OS显著更好，TA组的LCSS概率显著更低。匹配后，SR组的OS显著更长，TA组的LCSS概率更低。结论：对于局限性肝癌，SR比TA具有显著的生存获益。
Aim: To compare overall survival (OS) and liver cancer-specific survival (LCSS) in patients with localized hepatocellular carcinoma treated with surgical resection (SR) or thermal ablation (TA) using the Surveillance, Epidemiology and End Results database. Materials & methods: Kaplan-Meier, competing risk and Cox regression analyses were performed after identifying patients. Propensity score matching was then applied. Results: There was significantly better OS in the SR group and significantly lower probability of LCSS in the TA group. After matching, there was significantly longer OS in the SR group and a lower probability of LCSS in the TA group. Conclusion: SR offered a significant survival benefit over TA for localized hepatocellular carcinoma.