Colorectal cancer statistics, 2017

Colorectal cancer statistics, 2017
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DOI:
10.3322/caac.21395
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发表时间:
2017-05-01
影响因子:
254.7
通讯作者:
Jemal, Ahmedin
Jemal, Ahmedin
中科院分区:
医学1区
文献类型:
--
作者:
Siegel, Rebecca L.;Miller, Kimberly D.;Jemal, Ahmedin

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结直肠癌(CRC)是美国最常见的恶性肿瘤之一。每3年,美国癌症协会提供CRC发病率,生存率和死亡率和趋势的更新。截至2013年的发病率数据由监测,流行病学和最终结果计划,国家癌症登记计划和北美中央癌症登记协会提供。截至2014年的死亡率数据由国家卫生统计中心提供。CRC发病率在阿拉斯加土著和黑人中最高,在亚洲/太平洋岛民中最低,男性比女性高30%至40%。最近的时间模式在种族和性别上大体相似,但在年龄上有所不同。在2000年至2013年期间,50岁成年人的发病率下降了32%,其中65岁人群的远端肿瘤下降幅度最大(发病率比[IRR],0.50; 95%置信区间[95% CI],0.48-0.52),50 - 64岁年龄组直肠肿瘤最小(男性IRR,0.91; 95% CI,0.85-0.96;女性IRR,1.00; 95% CI,0.93-1.08)。2009年至2013年,除阿肯色州外,所有州50岁人群的总体CRC发病率均有所下降,7个州的年下降率超过5%;然而,大多数州50至64岁人群的直肠肿瘤发病率保持稳定。成年人中,
Colorectal cancer (CRC) is one of the most common malignancies in the United States. Every 3 years, the American Cancer Society provides an update of CRC incidence, survival, and mortality rates and trends. Incidence data through 2013 were provided by the Surveillance, Epidemiology, and End Results program, the National Program of Cancer Registries, and the North American Association of Central Cancer Registries. Mortality data through 2014 were provided by the National Center for Health Statistics. CRC incidence rates are highest in Alaska Natives and blacks and lowest in Asian/Pacific Islanders, and they are 30% to 40% higher in men than in women. Recent temporal patterns are generally similar by race and sex, but differ by age. Between 2000 and 2013, incidence rates in adults aged 50 years declined by 32%, with the drop largest for distal tumors in people aged 65 years (incidence rate ratio [IRR], 0.50; 95% confidence interval [95% CI], 0.48-0.52) and smallest for rectal tumors in ages 50 to 64 years (male IRR, 0.91; 95% CI, 0.85-0.96; female IRR, 1.00; 95% CI, 0.93-1.08). Overall CRC incidence in individuals ages 50 years declined from 2009 to 2013 in every state except Arkansas, with the decrease exceeding 5% annually in 7 states; however, rectal tumor incidence in those ages 50 to 64 years was stable in most states. Among adults aged