Serological characterization of Danish Haemophilus parasuis isolates

Serological characterization of Danish Haemophilus parasuis isolates
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DOI:
10.1016/j.vetmic.2004.07.013
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发表时间:
2004-11-15
影响因子:
3.3
通讯作者:
Mittal, KR
Mittal, KR
中科院分区:
农林科学2区
文献类型:
--
作者:
Angen, O;Svensmark, B;Mittal, KR

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与常规诊断相关,从病猪中收集了总共 103 株丹麦副猪嗜血杆菌现场分离株。使用间接血凝法 (IHA) 对分离株进行血清分型,其中 57 个分离株还通过免疫扩散进行血清分型。血清型 5 最为常见 (36%),其次是血清型 4 (13%) 和血清型 13 (22%),而 15% 的菌株无法通过 IHA 进行分型。血清型 1、2、6、7、9、12、14 和 15 仅由少数分离株代表。大多数丹麦分离株属于血清型,早期已被证明具有毒性。根据菌株是从全身性疾病(多发性浆膜炎、关节炎或脑膜炎)病例中分离出来还是仅在下呼吸道中发现,可以将菌株分为两组。观察到最显着差异的是血清型 4,与全身性感染相比,其在呼吸道疾病中的患病率更高,而对于不可分型的分离株,主要发现于全身性感染病例。 (C) 2004 年由 Elsevier B.V. 出版
A total of 103 Danish Haemophilus parasuis field isolates was collected from diseased pigs in connection with routine diagnostics. The isolates were serotyped using indirect haemagglutination (IHA) and for 57 of the isolates the serotyping was also performed by immunodiffusion. Serovar 5 was the most prevalent (36%), followed by serovar 4 (13%) and serovar 13 (22%), whereas 15% of the strains were nontypeable by IHA. Serovars 1, 2, 6, 7, 9, 12, 14, and 15 were only represented by a small number of isolates. Most of the Danish isolates belong to serovars, which earlier have been shown to be virulent. The strains could be divided into two groups depending on whether they were isolated from cases with systemic disease (polyserositis, arthritis or meningitis) or if they only were found in the lower respiratory tract. The most marked differences were observed for serovar 4, which had a higher prevalence in respiratory disease compared to systemic infection, and for the nontypeable isolates, which were mainly found in cases of systemic infection. (C) 2004 Published by Elsevier B.V.