Measurement of intracellular chloride ion concentration in ICC in situ and in explant culture
Measurement of intracellular chloride ion concentration in ICC in situ and in explant culture
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DOI：
10.1111/j.1365-2982.2010.01501.x
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发表时间：
2010-06
影响因子：
3.5
通讯作者：
Y. Zhu;S. Parsons;J. Huizinga
中科院分区：
文献类型：
--
作者：
Y. Zhu;S. Parsons;J. Huizinga
背景氯离子通道在Cajal间质细胞（ICC）的电起搏机制中起着重要作用。考虑这一作用的一个关键未知因素是氯平衡电位（ECl），由细胞内（[Cl−]i）和细胞外（[Cl−]o）氯离子的相对浓度确定。
Background Chloride channels are proposed to play a central role in the electrical pacemaking mechanism of interstitial cells of Cajal (ICC). A key unknown factor in the consideration of this role is the chloride equilibrium potential (ECl), as determined by the relative concentrations of intra‐ ([Cl−]i) and extracellular ([Cl−]o) chloride ions.