Adaptive Radiation Therapy (ART) Strategies and Technical Considerations: A State of the ART Review From NRG Oncology.
Adaptive Radiation Therapy (ART) Strategies and Technical Considerations: A State of the ART Review From NRG Oncology.
复制标题
DOI：
10.1016/j.ijrobp.2020.10.021
复制
发表时间：
2021-03-15
期刊：
影响因子：
--
通讯作者：
Wuthrick E
中科院分区：
文献类型：
--
作者：
Glide-Hurst CK;Lee P;Yock AD;Olsen JR;Cao M;Siddiqui F;Parker W;Doemer A;Rong Y;Kishan AU;Benedict SH;Li XA;Erickson BA;Sohn JW;Xiao Y;Wuthrick E
适应性放射治疗（ART）的整合，或在治疗过程中修改治疗计划，在临床实践中越来越广泛。抗逆转录病毒治疗具有很大的潜力，可以最大限度地减少治疗相关的毒性，同时根据对危险器官的剂量增加或减少目标剂量。然而，ART工作流程增加了放射治疗计划和交付过程的复杂性，可能带来额外的不确定性。这项工作旨在回顾目前可用的ART工作流程以及图像质量、可变形图像配准和剂量累积等技术考虑因素。描述了ART组件的质量保证考虑因素和最低建议。提供了人员和工作流程效率建议以及支持实施抗逆转录病毒治疗的现有临床证据摘要。最后，为了指导未来的临床试验方案，提供了一个ART医师指令示例和遵循标准NRG肿瘤学协议的物理模板。
The integration of adaptive radiation therapy (ART), or modifying the treatment plan during the treatment course, is becoming more widely available in clinical practice. ART offers strong potential for minimizing treatment-related toxicity while escalating or de-escalating target doses based on the dose to organs at risk. Yet, ART workflows add complexity into the radiation therapy planning and delivery process that may introduce additional uncertainties. This work sought to review presently available ART workflows as well as technological considerations such as image quality, deformable image registration, and dose accumulation. Quality assurance considerations for ART components and minimum recommendations are described. Personnel and workflow efficiency recommendations are provided as well as a summary of currently available clinical evidence supporting the implementation of ART. Finally, to guide future clinical trial protocols, an example ART physician directive and a physics template following standard NRG Oncology protocol is provided.
登录
查看更多内容
影响因子：
3.8
作者：
Brock, Kristy K.;Mutic, Sasa;Kessler, Marc L.
通讯作者：
Kessler, Marc L.
DOI：
10.1016/j.jmir.2020.05.001
发表时间：
2020-09-01
影响因子：
1.8
作者：
Hales, Rosie B.;Rodgers, John;Eccles, Cynthia L.
通讯作者：
Eccles, Cynthia L.
影响因子：
3.8
作者：
Chen, Guang-Pei;Ahunbay, Ergun;Li, X. Allen
通讯作者：
Li, X. Allen
影响因子：
2.1
作者：
Cunningham JM;Barberi EA;Miller J;Kim JP;Glide-Hurst CK
通讯作者：
Glide-Hurst CK
影响因子：
3.1
作者：
Dawson, Laura A.;Eccles, Cynthia;Craig, Tim
通讯作者：
Craig, Tim