Alteration of aquaporin mRNA expression after small bowel resection in the rat residual ileum and colon
Alteration of aquaporin mRNA expression after small bowel resection in the rat residual ileum and colon
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DOI：
10.1046/j.1440-1746.2003.03033.x
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发表时间：
2003-07
影响因子：
4.1
通讯作者：
T. Tsujikawa;A. Itoh;T. Fukunaga;J. Satoh;T. Yasuoka;Y. Fujiyama
中科院分区：
文献类型：
--
作者：
T. Tsujikawa;A. Itoh;T. Fukunaga;J. Satoh;T. Yasuoka;Y. Fujiyama
背景：小肠切除术后发生的腹泻由于肠道适应性而逐渐改善。已知几种水通道，称为水通道蛋白（AQP），在胃肠道中表达并促进水转运。然而，肠切除术后AQP的变化尚不清楚。本研究观察了大鼠小肠大部切除后残留回肠和结肠中水通道蛋白mRNA表达的变化。
Background: Diarrhea occurring after small bowel resection gradually improves due to intestinal adaptation. It is known that several water channels, termed aquaporins (AQP), are expressed in the gastrointestinal tract and facilitate water transport. However, the changes of AQP after bowel resection remain unclear. In the present paper, the alterations in AQP mRNA expression were investigated after a massive small bowel resection in the rat residual ileum and colon.