Preliminary crystallographic study of the Fab fragment of a monoclonal anti-phenylarsonate antibody.
Preliminary crystallographic study of the Fab fragment of a monoclonal anti-phenylarsonate antibody.
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单克隆抗苯胂酸抗体 Fab 片段的初步晶体学研究。
DOI：
10.1016/s0022-2836(83)80266-6
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发表时间：
1983
影响因子：
5.6
通讯作者：
Nisonoff,A
中科院分区：
文献类型：
--
作者：
Amit,AG;Harper,MM;Mariuzza,RA;Saludjian,P;Poljak,RJ;Lamoyi,E;Nisonoff,A
给出了抗对苯基砷酸盐单抗Fab片段的初步结晶学数据。该晶状Fab片段是通过筛选从A/J免疫脾细胞与非分泌性小鼠骨髓瘤细胞系杂交获得的一些抗ARSATA单抗而发现的。该蛋白质属单斜晶系，空间群为P21，晶胞参数为a=86·2±0·1，b=80·4±0·2，c=75·8±0·1，β=90·3±0·1°。进动照片显示，X射线反射的分辨率可达3？
Preliminary crystallographic data are given for the Fab fragment of a monoclonal anti-p-phenylarsonate antibody. This crystalline Fab fragment was found by screening a number of monoclonal anti-arsonate antibodies obtained from hybrids of A/J immune spleen cells with a non-secreting mouse myeloma line. The protein crystallizes in the monoclinic space groupP21witha= 86·2 ± 0·1 Å,b= 80·4±0·2 Å,c= 75·8±0·1 Å, β = 90·3±0·1 °. Precession photographs show X-ray reflections extending to a resolution of 3 Å.