Rare primary rectal mucosa-associated lymphoid tissue lymphoma with curative resection by endoscopic submucosal dissection: A case report and review of literature.

Rare primary rectal mucosa-associated lymphoid tissue lymphoma with curative resection by endoscopic submucosal dissection: A case report and review of literature.
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DOI:
10.12998/wjcc.v10.i21.7599
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发表时间:
2022-07-26
影响因子:
1.1
通讯作者:
--
中科院分区:
医学4区
文献类型:
--
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粘膜相关淋巴组织结外边缘区淋巴瘤(MALT淋巴瘤)发生在约9%的非霍奇金B细胞淋巴瘤中。胃肠道是原发性非霍奇金淋巴瘤结节型最常见的受累部位。然而,它很少发生在直肠内,目前对其诊断和治疗尚无共识。我们报告一个罕见的侧向扩散性肿瘤样直肠MALT淋巴瘤病例,其诊断和浸润深度是通过放大内镜和超声内镜确定的。然后,病变整块切除内镜黏膜下剥离术(ESD)单独。经苏木精-伊红染色、免疫组化染色及基因排列分析证实为MALT淋巴瘤。监测检查表明该患者无病生存2年。我们报告了一个罕见的原发性直肠MALT淋巴瘤,可通过ESD切除术治愈。ESD是直肠MALT淋巴瘤安全有效的治疗选择。
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) occurs in approximately 9% of non-Hodgkin B-cell lymphomas. The gastrointestinal tract is the most commonly affected site of the extranodal forms of primary non-Hodgkin’s lymphomas. However, it rarely occurs within the rectum, and at present, there is no consensus on its diagnosis and treatment at this site. We report a rare laterally spreading tumour-like rectal MALT lymphoma case in which the diagnosis and the depth of infiltration were determined by magnifying endoscopy and ultrasonic endoscopy. Then, the lesion was en bloc resected by endoscopic submucosal dissection (ESD) alone. The lesion was confirmed as MALT lymphoma by haematoxylin and eosin staining, immunohistochemical staining and gene arrangement analysis. Surveillance exams have indicated a 2-year disease-free survival for this patient. We report a rare primary rectal MALT lymphoma that was curable with resection by ESD. ESD is a safe and effective therapeutic option for rectal MALT lymphoma.
DOI: 10.1159/000154814
发表时间: 2008-09-30
影响因子: 0.6
作者:
Kanneganti K;Balar B
通讯作者: Balar B