Medical and Biomedical Applications of Shock Waves

Medical and Biomedical Applications of Shock Waves
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冲击波的医学和生物医学应用

DOI:
10.1007/978-3-319-47570-7
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发表时间:
2016
期刊:
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影响因子:
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通讯作者:
A. Loske
A. Loske
中科院分区:
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文献类型:
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作者:
A. Loske

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这本书的目的是扩大读者的知识范围,关于在医学和生物学中使用冲击波,以及有助于更安全,更有效的治疗和鼓励科学研究。对专家来说,这可能是一种刺激,促使他们产生创新的想法,并向同事和学生介绍新的主题。每一章都写得尽可能流畅,没有连续的中断来查找专业术语的含义。然而,很难决定哪些术语应被视为“专门”或“不明显”,哪些词语是大多数学者文化遗产的一部分。根据不同的背景,读者可能会跳过本书的某些部分,将其作为参考,以查找已发表研究的具体数据或细节,需要来自物理学、数学、生物学、医学、工程学和化学等多个领域的专家合作,以开发生物医学改进并实施实验和临床方案。这种团队合作的需要增加了研究人员理解属于与其专业领域不同的领域的概念的必要性;然而,由于缺乏非专业人员的参考书目,并且需要时间参与不熟悉的主题,学习过程可能很困难。这本书的目标之一是促进科学家之间的互动,例如,分子生物学家可以与流体动力学专家进行富有成效的谈话,讨论如何利用声空化来遗传转化肿瘤细胞,或者泌尿科医生和计算机工程师可以分析算法来预测体外碎石术的成功结果。本书的某些章节也可作为撰写科学论文时的参考。有趣但也令人担忧的是,聚焦冲击波和径向压力波的临床应用早在所涉及的基本现象被完全理解之前就开始了。这方面的证据是在首次临床应用多年后发表的大量报告体外和体内实验的文章。科学界和临床设备制造商的基本责任是显而易见的。进一步研究以更好地了解压力波与活组织和细胞的相互作用,
This book was written with the aim of widening the reader’s spectrum of knowledge regarding the uses of shock waves in medicine and biology, as well as to contribute to safer and more efficient treatments and encourage scientific research. For experts, it may be a stimulus to generate innovative ideas and introduce their colleagues and students to novel topics. Each chapter was written to be read as smoothly as possible, without continuous interruptions to look up the meanings of specialized terms. Nevertheless, it was difficult to decide which terms should be considered as “specialized” or “not obvious” and which words are part of the cultural heritage of most academicians. Depending on his background, the reader may want to skip certain sections of this book, keeping them as a reference to look up specific data or details on published research.Collaborations between specialists from several areas, such as physics, mathematics, biology, medicine, engineering, and chemistry, are required to develop biomedical improvements and implement experimental and clinical protocols. This need for teamwork has increased the necessity for researchers to understand concepts belonging to areas that are different from their field of expertise; however, the learning process may be difficult due to the lack of a bibliography for nonspecialists and because of the time demanded to become involved in unfamiliar topics. One of the goals of this book is to foster interactions between scientists so that, for instance, a molecular biologist may have a fruitful talk with a specialist in fluid dynamics about how to take advantage of acoustic cavitation to genetically transform tumor cells or so that a urologist and a computer engineer can analyze algorithms to predict successful outcomes in extracorporeal lithotripsy. Some sections of this book may also serve as a reference during the writing of scientific papers. It is interesting but also worrisome that the clinical use of focused shock waves and radial pressure waves started long before the basic phenomena involved were fully understood. Evidence of this is the vast number of articles reporting in vitro and in vivo experiments published many years after the first clinical application. The underlying responsibility of the scientific community and the manufacturers of clinical equipment is evident. Further research to better understand the interactions of pressure waves with living tissue and cells will certainly lead to safer