Congenital heart diseases in the boxer dog:: A retrospective study of 105 cases (1998-2005)

Congenital heart diseases in the boxer dog:: A retrospective study of 105 cases (1998-2005)
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DOI:
10.1111/j.1439-0442.2006.00865.x
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发表时间:
2006-09-01
期刊:
JOURNAL OF VETERINARY MEDICINE SERIES A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE
影响因子:
--
通讯作者:
Pouchelon, J. -L.
Pouchelon, J. -L.
中科院分区:
其他
文献类型:
--
作者:
Chetboul, V.;Trolle, J. M.;Pouchelon, J. -L.

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主动脉瓣下狭窄(SAS)是犬最常见的先天性心脏病(CHD)之一,主要累及拳师犬。然而,现代诊断成像系统的日益可用性现在允许更好地评估心脏形态和功能,从而促进清醒动物中CHD的早期检测。在这种情况下,病例记录的拳击手狗诊断为冠心病使用超声心动图结合多普勒模式,回顾性审查(1998年至2005年)。105名拳击运动员中,有53名(50.5%)为单一CHD,52名(49.5%)为合并CHD。最常见的CHD是在这些动物中的56.2%(59/105)中观察到的房间隔缺损(ASD),其次是二尖瓣发育不良(58/105,55.2%)和SAS(49/105,46.7%)。29.5%(31/105)的患者合并1 ~ 2例冠心病。大多数具有低强度左心脏底部收缩期杂音的犬有孤立的ASD,而大多数具有类似但高强度杂音的犬有SAS,孤立或与并发CHD相关。Boxer犬ASD和二尖瓣发育不良的发生率高于以前的假设,ASD是该品种犬左心底部收缩期杂音的常见原因。这证实了这种杂音的检测不应作为SAS诊断确认的唯一标准。
Subaortic stenosis (SAS) is one of the most common congenital heart diseases (CHD) in dogs with Boxers being predominantly affected. However, the increasing availability of modern diagnostic imaging systems now allows a better assessment of cardiac morphology and function, thereby facilitating early detection of CHD in awake animals. In this context, the case records of Boxer dogs diagnosed with CHD using echocardiography combined with Doppler mode, were retrospectively reviewed (1998-2005). One hundred and five Boxers exhibiting either a single CHD (53/105, 50.5%) or association of several CHD (52/105,49.5%) were included. The most common CHD was atrial septal defect (ASD) observed in 56.2% of these animals (59/105), followed by mitral dysplasia (58/105, 55.2%), and SAS (49/105, 46.7%). SAS was associated with one or two CHD in 29.5% of cases (31/105). Most of the dogs with a low intensity left heart base systolic murmur had an isolated ASD whereas most of the dogs with a similar but high intensity murmur had SAS, either isolated or associated with a concurrent CHD. The incidence of ASD and mitral dysplasia in Boxer dogs is higher than previously assumed, and ASD is a common cause of left heart base systolic murmur in this breed of dog. This confirms that the detection of such a murmur should not be used as the unique criterion for diagnostic confirmation of SAS.