Methotrexate resistance in al L1210 cell line resulting from increased dihydrofolate reductase, decreased thymidylate synthetase activity, and normal membrane transport. Computer simulations based on network thermodynamics.
Methotrexate resistance in al L1210 cell line resulting from increased dihydrofolate reductase, decreased thymidylate synthetase activity, and normal membrane transport. Computer simulations based on network thermodynamics.
复制标题
所有 L1210 细胞系中的甲氨蝶呤耐药性是由于二氢叶酸还原酶增加、胸苷酸合成酶活性降低和膜转运正常所致。
DOI:
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发表时间:
1981
期刊:
影响因子:
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通讯作者:
Goldman,ID
中科院分区:
文献类型:
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作者:
White,JC;Goldman,ID